Comparative effectiveness of disease-modifying therapies for highly active relapsing-remitting multiple sclerosis despite previous treatment – a systematic review and network meta-analysis

Comparative effectiveness of disease-modifying therapies for highly active relapsing-remitting multiple sclerosis despite previous treatment – a systematic review and network meta-analysis

Abstract Background Comparative assessments of all available disease-modifying therapies (DMTs) in patients with highly active relapsing-remitting multiple sclerosis (RRMS) are lacking, even though some of these DMTs are restricted to this MS subpopulation. We therefore aimed to compare DMTs in pati...

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Bibliographic Details
Main Authors: Michael Köhler, Friedemann Paul, Kirsten Janke, Sibylle Sturtz, Daniela Preukschat, Sabine Ostlender, Michaela Florina Kerekes, Thomas Kaiser
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Neurology
Subjects:
Multiple sclerosis
High disease activity
Data availability
Systematic review
Online Access:https://doi.org/10.1186/s12883-025-04338-7
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