Posterior breast cancer: Mammographic and ultrasonographic features
Background/Aim. Posterior breast cancers are located in the prepectoral region of the breast. Owing to this distinctive anatomical localization, physical examination and mammographic or ultrasonographic evaluation can be difficult. The purpose of the study was to assess possibilities of diagnosti...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2013-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501300032J.pdf |
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| author | Janković Ana Nadrljanski Mirjan Plešinac-Karapandžić Vesna Ivanović Nebojša Radojičić Zoran Milošević Zorica |
| author_facet | Janković Ana Nadrljanski Mirjan Plešinac-Karapandžić Vesna Ivanović Nebojša Radojičić Zoran Milošević Zorica |
| author_sort | Janković Ana |
| collection | DOAJ |
| description | Background/Aim. Posterior breast cancers are located in the prepectoral region of the breast. Owing to this distinctive anatomical localization, physical examination and mammographic or ultrasonographic evaluation can be difficult. The purpose of the study was to assess possibilities of diagnostic mammography and breast ultrasonography in detection and differentiation of posterior breast cancers. Methods. The study included 40 women with palpable, histopathological confirmed posterior breast cancer. Mammographic and ultrasonographic features were defined according to Breast Imaging Reporting and Data System (BI-RADS) lexicon. Results. Based on standard two-view mammography 87.5%, of the cases were classified as BI-RADS 4 and 5 categories, while after additional mammographic views all the cases were defined as BIRADS 4 and 5 categories. Among 96 mammographic descriptors, the most frequent were: spiculated mass (24.0%), architectural distortion (16.7%), clustered microcalcifications (12.6%) and focal asymmetric density (12.6%). The differentiation of the spiculated mass was significantly associated with the possibility to visualize the lesion at two-view mammography (p = 0.009), without the association with lesion diameter (p = 0.083) or histopathological type (p = 0.055). Mammographic signs of invasive lobular carcinoma were significantly different from other histopathological types (architectural distortion, p = 0.003; focal asymmetric density, p = 0.019; association of four or five subtle signs of malignancy, p = 0.006). All cancers were detectable by ultrasonography. Mass lesions were found in 82.0% of the cases. Among 153 ultrasonographic descriptors, the most frequent were: irregular mass (15.7%), lobulated mass (7.2%), abnormal color Doppler signals (20.3%), posterior acoustic attenuation (18.3%). Ultrasonographic BI-RADS 4 and 5 categories were defined in 72.5% of the cases, without a significant difference among various histopathological types (p = 0.109). Conclusion. Standard two-view mammography followed by additional mammographic projections is an effective way to demonstrate the spiculated mass and to classify the prepectoral lesion as category BI-RADS 4 or 5. Additional ultrasonography can overcome the mimicry of invasive lobular breast carcinoma at mammography. |
| format | Article |
| id | doaj-art-98e12ca9d7ae407e9dcdfc0c70ac8f12 |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-98e12ca9d7ae407e9dcdfc0c70ac8f122025-08-20T03:19:49ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502013-01-0170111034103810.2298/VSP120726032JPosterior breast cancer: Mammographic and ultrasonographic featuresJanković AnaNadrljanski MirjanPlešinac-Karapandžić VesnaIvanović NebojšaRadojičić ZoranMilošević ZoricaBackground/Aim. Posterior breast cancers are located in the prepectoral region of the breast. Owing to this distinctive anatomical localization, physical examination and mammographic or ultrasonographic evaluation can be difficult. The purpose of the study was to assess possibilities of diagnostic mammography and breast ultrasonography in detection and differentiation of posterior breast cancers. Methods. The study included 40 women with palpable, histopathological confirmed posterior breast cancer. Mammographic and ultrasonographic features were defined according to Breast Imaging Reporting and Data System (BI-RADS) lexicon. Results. Based on standard two-view mammography 87.5%, of the cases were classified as BI-RADS 4 and 5 categories, while after additional mammographic views all the cases were defined as BIRADS 4 and 5 categories. Among 96 mammographic descriptors, the most frequent were: spiculated mass (24.0%), architectural distortion (16.7%), clustered microcalcifications (12.6%) and focal asymmetric density (12.6%). The differentiation of the spiculated mass was significantly associated with the possibility to visualize the lesion at two-view mammography (p = 0.009), without the association with lesion diameter (p = 0.083) or histopathological type (p = 0.055). Mammographic signs of invasive lobular carcinoma were significantly different from other histopathological types (architectural distortion, p = 0.003; focal asymmetric density, p = 0.019; association of four or five subtle signs of malignancy, p = 0.006). All cancers were detectable by ultrasonography. Mass lesions were found in 82.0% of the cases. Among 153 ultrasonographic descriptors, the most frequent were: irregular mass (15.7%), lobulated mass (7.2%), abnormal color Doppler signals (20.3%), posterior acoustic attenuation (18.3%). Ultrasonographic BI-RADS 4 and 5 categories were defined in 72.5% of the cases, without a significant difference among various histopathological types (p = 0.109). Conclusion. Standard two-view mammography followed by additional mammographic projections is an effective way to demonstrate the spiculated mass and to classify the prepectoral lesion as category BI-RADS 4 or 5. Additional ultrasonography can overcome the mimicry of invasive lobular breast carcinoma at mammography.http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501300032J.pdfbreast neoplasmsmammographyultrasonographysensitivity and specificity |
| spellingShingle | Janković Ana Nadrljanski Mirjan Plešinac-Karapandžić Vesna Ivanović Nebojša Radojičić Zoran Milošević Zorica Posterior breast cancer: Mammographic and ultrasonographic features Vojnosanitetski Pregled breast neoplasms mammography ultrasonography sensitivity and specificity |
| title | Posterior breast cancer: Mammographic and ultrasonographic features |
| title_full | Posterior breast cancer: Mammographic and ultrasonographic features |
| title_fullStr | Posterior breast cancer: Mammographic and ultrasonographic features |
| title_full_unstemmed | Posterior breast cancer: Mammographic and ultrasonographic features |
| title_short | Posterior breast cancer: Mammographic and ultrasonographic features |
| title_sort | posterior breast cancer mammographic and ultrasonographic features |
| topic | breast neoplasms mammography ultrasonography sensitivity and specificity |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501300032J.pdf |
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