Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy Adolescents
<b>Background/Objectives:</b> We aimed to investigate the influence of cardiorespiratory fitness (CRF) and body composition on arterial stiffness. <b>Methods:</b> Carotid-to-femoral pulse wave velocity (cfPWV) and aortic systolic (ASBP) and diastolic (ADBP) blood pressure wer...
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2024-09-01
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| author | Hwan Kim Scott R. Collier Valerio Bonavolontà Austin Lassiter Seaver Wait Marco Meucci |
| author_facet | Hwan Kim Scott R. Collier Valerio Bonavolontà Austin Lassiter Seaver Wait Marco Meucci |
| author_sort | Hwan Kim |
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| description | <b>Background/Objectives:</b> We aimed to investigate the influence of cardiorespiratory fitness (CRF) and body composition on arterial stiffness. <b>Methods:</b> Carotid-to-femoral pulse wave velocity (cfPWV) and aortic systolic (ASBP) and diastolic (ADBP) blood pressure were compared between upper and lower tertiles of oxygen consumption at the aerobic threshold (VO<sub>2AerT</sub>), peak oxygen consumption (VO<sub>2peak</sub>), percentage of fat mass (FM%), and body mass index (BMI) in sixty adolescents (30 males and 30 females, 14.9 ± 2.1 years old). A stepwise multivariable linear regression analysis was performed to investigate the independent associations between VO<sub>2AerT</sub> and VO<sub>2peak</sub> and cfPWV, and between BMI and FM% and cfPWV with adjustments for age, sex, ASBP, and ADBP. <b>Results:</b> cfPWV and ADBP were lower in the second and third VO<sub>2AerT</sub> tertiles compared to the first tertile (cfPWV, 4.7 ± 0.5 and 4.7 ± 0.5 vs. 5.3 ± 0.8 m/s, <i>p</i> < 0.01; ADBP, 62 ± 7 and 62 ± 7 vs. 70 ± 8 mmHg, <i>p</i> < 0.01). ASBP was lower in the third VO<sub>2AerT</sub> tertile compared to the first tertile (94 ± 7 vs. 101 ± 12 mmHg, <i>p</i> = 0.05). ADBP was lower in the second VO<sub>2peak</sub> tertile compared to the first tertile (62 ± 7 vs. 68 ± 9 mmHg, <i>p</i> = 0.03). ASBP was lower in the first and second BMI tertiles compared to the third tertile (95 ± 8 and 95 ± 7 vs. 102 ± 11 mmHg, <i>p</i> = 0.02). The eight-variable model significantly contributed to the variance of cfPWV (F(8, 51) = 7.450, <i>p</i> < 0.01), accounting for 47% of the variance. Individually, age (<i>p</i> < 0.05) and ADBP (<i>p</i> < 0.01) significantly predicted cfPWV. <b>Conclusions:</b> Submaximal indicators of CRF such as VO<sub>2AerT</sub> should be considered as a part of the risk stratification of cardiovascular disease in healthy adolescents. |
| format | Article |
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| institution | OA Journals |
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| language | English |
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| spelling | doaj-art-98d93404cd7b4077a95483aa9fc0a97a2025-08-20T01:55:22ZengMDPI AGChildren2227-90672024-09-01119107810.3390/children11091078Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy AdolescentsHwan Kim0Scott R. Collier1Valerio Bonavolontà2Austin Lassiter3Seaver Wait4Marco Meucci5Department of Public Health and Exercise Science, Appalachian State University, Boone, NC 28608, USADepartment of Public Health and Exercise Science, Appalachian State University, Boone, NC 28608, USADepartment of Biotechnological and Applied Clinical Sciences, University of L’Aquila, 67100 L’Aquila, ItalyDepartment of Public Health and Exercise Science, Appalachian State University, Boone, NC 28608, USADepartment of Public Health and Exercise Science, Appalachian State University, Boone, NC 28608, USADepartment of Public Health and Exercise Science, Appalachian State University, Boone, NC 28608, USA<b>Background/Objectives:</b> We aimed to investigate the influence of cardiorespiratory fitness (CRF) and body composition on arterial stiffness. <b>Methods:</b> Carotid-to-femoral pulse wave velocity (cfPWV) and aortic systolic (ASBP) and diastolic (ADBP) blood pressure were compared between upper and lower tertiles of oxygen consumption at the aerobic threshold (VO<sub>2AerT</sub>), peak oxygen consumption (VO<sub>2peak</sub>), percentage of fat mass (FM%), and body mass index (BMI) in sixty adolescents (30 males and 30 females, 14.9 ± 2.1 years old). A stepwise multivariable linear regression analysis was performed to investigate the independent associations between VO<sub>2AerT</sub> and VO<sub>2peak</sub> and cfPWV, and between BMI and FM% and cfPWV with adjustments for age, sex, ASBP, and ADBP. <b>Results:</b> cfPWV and ADBP were lower in the second and third VO<sub>2AerT</sub> tertiles compared to the first tertile (cfPWV, 4.7 ± 0.5 and 4.7 ± 0.5 vs. 5.3 ± 0.8 m/s, <i>p</i> < 0.01; ADBP, 62 ± 7 and 62 ± 7 vs. 70 ± 8 mmHg, <i>p</i> < 0.01). ASBP was lower in the third VO<sub>2AerT</sub> tertile compared to the first tertile (94 ± 7 vs. 101 ± 12 mmHg, <i>p</i> = 0.05). ADBP was lower in the second VO<sub>2peak</sub> tertile compared to the first tertile (62 ± 7 vs. 68 ± 9 mmHg, <i>p</i> = 0.03). ASBP was lower in the first and second BMI tertiles compared to the third tertile (95 ± 8 and 95 ± 7 vs. 102 ± 11 mmHg, <i>p</i> = 0.02). The eight-variable model significantly contributed to the variance of cfPWV (F(8, 51) = 7.450, <i>p</i> < 0.01), accounting for 47% of the variance. Individually, age (<i>p</i> < 0.05) and ADBP (<i>p</i> < 0.01) significantly predicted cfPWV. <b>Conclusions:</b> Submaximal indicators of CRF such as VO<sub>2AerT</sub> should be considered as a part of the risk stratification of cardiovascular disease in healthy adolescents.https://www.mdpi.com/2227-9067/11/9/1078pulse wave velocitycardiorespiratory fitnessbody mass indexfat massadolescents |
| spellingShingle | Hwan Kim Scott R. Collier Valerio Bonavolontà Austin Lassiter Seaver Wait Marco Meucci Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy Adolescents Children pulse wave velocity cardiorespiratory fitness body mass index fat mass adolescents |
| title | Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy Adolescents |
| title_full | Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy Adolescents |
| title_fullStr | Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy Adolescents |
| title_full_unstemmed | Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy Adolescents |
| title_short | Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy Adolescents |
| title_sort | cardiorespiratory fitness is an indicator of arterial stiffness and aortic blood pressure in healthy adolescents |
| topic | pulse wave velocity cardiorespiratory fitness body mass index fat mass adolescents |
| url | https://www.mdpi.com/2227-9067/11/9/1078 |
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