ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES
The influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resi...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2014-11-01
|
| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/1841 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849251574608560128 |
|---|---|
| author | V. .. Sviridov Ya. G. Razuvaeva L. N. Shantanova |
| author_facet | V. .. Sviridov Ya. G. Razuvaeva L. N. Shantanova |
| author_sort | V. .. Sviridov |
| collection | DOAJ |
| description | The influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resistance of the experimental animals to hypoxias of different genesis. S. centauroides in the dose of 150 mg/kg has the most pronounced antihypoxic activity, increasing the lifespan of the animals with hemic and normobaric hypoxia on average by 60 % (p < 0,001) and and with histotoxic hypoxia - by 50 % (p < 0,001). |
| format | Article |
| id | doaj-art-98d4001f9d0b41408af1c79d1999a73c |
| institution | Kabale University |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| publishDate | 2014-11-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj-art-98d4001f9d0b41408af1c79d1999a73c2025-08-20T03:56:54ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962014-11-010677791787ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDESV. .. Sviridov0Ya. G. Razuvaeva1L. N. Shantanova2Institute of General and Experimental Biology SB RASInstitute of General and Experimental Biology SB RASInstitute of General and Experimental Biology SB RASThe influence of the dry extract from Serratula centauroides roots on the resistance to the hemic, hystotoxic and hypercapnic hypoxias was investigated in the experiments on white rats. It was established that the course administration of the remedy in the doses of50,100,150 mg/kg increases the resistance of the experimental animals to hypoxias of different genesis. S. centauroides in the dose of 150 mg/kg has the most pronounced antihypoxic activity, increasing the lifespan of the animals with hemic and normobaric hypoxia on average by 60 % (p < 0,001) and and with histotoxic hypoxia - by 50 % (p < 0,001).https://www.actabiomedica.ru/jour/article/view/1841serratula centauroidesserratula centauroideshypoxic statesantihypoxic action |
| spellingShingle | V. .. Sviridov Ya. G. Razuvaeva L. N. Shantanova ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES Acta Biomedica Scientifica serratula centauroides serratula centauroides hypoxic states antihypoxic action |
| title | ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES |
| title_full | ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES |
| title_fullStr | ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES |
| title_full_unstemmed | ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES |
| title_short | ANTIHYPOXIC PROPERTIES OF THE DRY EXTRACT FROM SERRATULA CENTAUROIDES |
| title_sort | antihypoxic properties of the dry extract from serratula centauroides |
| topic | serratula centauroides serratula centauroides hypoxic states antihypoxic action |
| url | https://www.actabiomedica.ru/jour/article/view/1841 |
| work_keys_str_mv | AT vsviridov antihypoxicpropertiesofthedryextractfromserratulacentauroides AT yagrazuvaeva antihypoxicpropertiesofthedryextractfromserratulacentauroides AT lnshantanova antihypoxicpropertiesofthedryextractfromserratulacentauroides |