Jerky Movement with Ceftazidime: A Case of Ceftazidime-Induced Neurotoxicity with a Review of the Literature
Neurotoxicity manifested as confusion and seizures has been recognized as a side effect of multiple cephalosporins including ceftazidime. Renal impairment and inappropriate dosing are the most common contributors to the development of neurological abnormalities in patients receiving these antibiotic...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/8936478 |
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| author | Mohammed Al-Sadawi Romy Rodriguez Ortega Natalie Sun Madina Abdurahimova Samy I. McFarlane |
| author_facet | Mohammed Al-Sadawi Romy Rodriguez Ortega Natalie Sun Madina Abdurahimova Samy I. McFarlane |
| author_sort | Mohammed Al-Sadawi |
| collection | DOAJ |
| description | Neurotoxicity manifested as confusion and seizures has been recognized as a side effect of multiple cephalosporins including ceftazidime. Renal impairment and inappropriate dosing are the most common contributors to the development of neurological abnormalities in patients receiving these antibiotics. The presence of baseline neurological abnormalities likely contributes to the frequency of these adverse events. Here, we present a case of a 78-year-old man that developed altered mental status and myoclonic movement after initiation of ceftazidime in the setting of mild renal dysfunction. Resolution of clinical picture was evident after 48 hours of discontinuation of the antibiotic without additional interventions. |
| format | Article |
| id | doaj-art-98d2670780d4434185e39f807623b3a1 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-98d2670780d4434185e39f807623b3a12025-02-03T01:03:33ZengWileyCase Reports in Medicine1687-96271687-96352019-01-01201910.1155/2019/89364788936478Jerky Movement with Ceftazidime: A Case of Ceftazidime-Induced Neurotoxicity with a Review of the LiteratureMohammed Al-Sadawi0Romy Rodriguez Ortega1Natalie Sun2Madina Abdurahimova3Samy I. McFarlane4Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, NY 11203, USADepartment of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, NY 11203, USADepartment of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, NY 11203, USADepartment of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, NY 11203, USADepartment of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, NY 11203, USANeurotoxicity manifested as confusion and seizures has been recognized as a side effect of multiple cephalosporins including ceftazidime. Renal impairment and inappropriate dosing are the most common contributors to the development of neurological abnormalities in patients receiving these antibiotics. The presence of baseline neurological abnormalities likely contributes to the frequency of these adverse events. Here, we present a case of a 78-year-old man that developed altered mental status and myoclonic movement after initiation of ceftazidime in the setting of mild renal dysfunction. Resolution of clinical picture was evident after 48 hours of discontinuation of the antibiotic without additional interventions.http://dx.doi.org/10.1155/2019/8936478 |
| spellingShingle | Mohammed Al-Sadawi Romy Rodriguez Ortega Natalie Sun Madina Abdurahimova Samy I. McFarlane Jerky Movement with Ceftazidime: A Case of Ceftazidime-Induced Neurotoxicity with a Review of the Literature Case Reports in Medicine |
| title | Jerky Movement with Ceftazidime: A Case of Ceftazidime-Induced Neurotoxicity with a Review of the Literature |
| title_full | Jerky Movement with Ceftazidime: A Case of Ceftazidime-Induced Neurotoxicity with a Review of the Literature |
| title_fullStr | Jerky Movement with Ceftazidime: A Case of Ceftazidime-Induced Neurotoxicity with a Review of the Literature |
| title_full_unstemmed | Jerky Movement with Ceftazidime: A Case of Ceftazidime-Induced Neurotoxicity with a Review of the Literature |
| title_short | Jerky Movement with Ceftazidime: A Case of Ceftazidime-Induced Neurotoxicity with a Review of the Literature |
| title_sort | jerky movement with ceftazidime a case of ceftazidime induced neurotoxicity with a review of the literature |
| url | http://dx.doi.org/10.1155/2019/8936478 |
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