Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder

Cortical macro- and microstructural changes in isolated rapid eye movement sleep behavior disorder

Abstract Cortical mean diffusivity (cMD), a marker of cortical microstructural changes in neurodegenerative disorders, remains unexplored in isolated REM sleep behavior disorder (iRBD), a prodromal stage of Lewy body (LB) diseases. Its relationship with cortical thickness (CTh), clinical features, a...

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Main Authors: Jèssica Pardo, Ignacio Roura, Victor Montal, Cristina Martín-Barceló, Javier Oltra, Anna Campabadal, Núria Bargalló, Mònica Serradell, Gerard Mayà, Angelica Montini, Carles Gaig, Claustre Pont-Sunyer, Juan Fortea, Alex Iranzo, Carme Junqué, Bàrbara Segura
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01058-0
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