A comparison of nonlinear filtering approaches in the context of anHIV model

In this paper three different filtering methods, the ExtendedKalman Filter (EKF), the Gauss-Hermite Filter (GHF), and theUnscented Kalman Filter (UKF), are compared for state-only andcoupled state and parameter estimation when used with log statevariables of a model of the immunologic response to th...

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Main Authors: H. Thomas Banks, Shuhua Hu, Zackary R. Kenz, Hien T. Tran
Format: Article
Language:English
Published: AIMS Press 2010-03-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.213
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author H. Thomas Banks
Shuhua Hu
Zackary R. Kenz
Hien T. Tran
author_facet H. Thomas Banks
Shuhua Hu
Zackary R. Kenz
Hien T. Tran
author_sort H. Thomas Banks
collection DOAJ
description In this paper three different filtering methods, the ExtendedKalman Filter (EKF), the Gauss-Hermite Filter (GHF), and theUnscented Kalman Filter (UKF), are compared for state-only andcoupled state and parameter estimation when used with log statevariables of a model of the immunologic response to the humanimmunodeficiency virus (HIV) in individuals. The filters areimplemented to estimate model states as well as model parametersfrom simulated noisy data, and are compared in terms of estimationaccuracy and computational time. Numerical experiments reveal thatthe GHF is the most computationally expensive algorithm, while theEKF is the least expensive one. In addition, computationalexperiments suggest that there is little difference in theestimation accuracy between the UKF and GHF. When measurements aretaken as frequently as every week to two weeks, the EKF is thesuperior filter. When measurements are further apart, the UKF is thebest choice in the problem under investigation.
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institution Kabale University
issn 1551-0018
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publishDate 2010-03-01
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series Mathematical Biosciences and Engineering
spelling doaj-art-98d1303868594b40a0a87b5a7d0a963a2025-01-24T02:00:28ZengAIMS PressMathematical Biosciences and Engineering1551-00182010-03-017221323610.3934/mbe.2010.7.213A comparison of nonlinear filtering approaches in the context of anHIV modelH. Thomas Banks0Shuhua Hu1Zackary R. Kenz2Hien T. Tran3Center for Research in Scientific Computation, Raleigh, NC 27695-8205Center for Research in Scientific Computation, Raleigh, NC 27695-8205Center for Research in Scientific Computation, Raleigh, NC 27695-8205Center for Research in Scientific Computation, Raleigh, NC 27695-8205In this paper three different filtering methods, the ExtendedKalman Filter (EKF), the Gauss-Hermite Filter (GHF), and theUnscented Kalman Filter (UKF), are compared for state-only andcoupled state and parameter estimation when used with log statevariables of a model of the immunologic response to the humanimmunodeficiency virus (HIV) in individuals. The filters areimplemented to estimate model states as well as model parametersfrom simulated noisy data, and are compared in terms of estimationaccuracy and computational time. Numerical experiments reveal thatthe GHF is the most computationally expensive algorithm, while theEKF is the least expensive one. In addition, computationalexperiments suggest that there is little difference in theestimation accuracy between the UKF and GHF. When measurements aretaken as frequently as every week to two weeks, the EKF is thesuperior filter. When measurements are further apart, the UKF is thebest choice in the problem under investigation.https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.213hiv.gauss-hermite filterunscented kalman filterextended kalman filter
spellingShingle H. Thomas Banks
Shuhua Hu
Zackary R. Kenz
Hien T. Tran
A comparison of nonlinear filtering approaches in the context of anHIV model
Mathematical Biosciences and Engineering
hiv.
gauss-hermite filter
unscented kalman filter
extended kalman filter
title A comparison of nonlinear filtering approaches in the context of anHIV model
title_full A comparison of nonlinear filtering approaches in the context of anHIV model
title_fullStr A comparison of nonlinear filtering approaches in the context of anHIV model
title_full_unstemmed A comparison of nonlinear filtering approaches in the context of anHIV model
title_short A comparison of nonlinear filtering approaches in the context of anHIV model
title_sort comparison of nonlinear filtering approaches in the context of anhiv model
topic hiv.
gauss-hermite filter
unscented kalman filter
extended kalman filter
url https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.213
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