<i>ARID2</i> Deficiency Enhances Tumor Progression via ERBB3 Signaling in <i>TFE3</i>-Rearranged Renal Cell Carcinoma

<i>ARID2</i> Deficiency Enhances Tumor Progression via ERBB3 Signaling in <i>TFE3</i>-Rearranged Renal Cell Carcinoma

<i>TFE3</i>-rearranged Renal Cell Carcinoma (TFE3-RCC) is an aggressive subtype of RCC characterized by Xp11.2 rearrangement, leading to TFE3 fusion proteins with oncogenic potential. Despite advances in understanding its molecular biology, effective therapies for advanced cases remain e...

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Bibliographic Details
Main Authors: Jinglong Tang, Shintaro Funasaki, Hidekazu Nishizawa, Shoichiro Kuroda, Takanobu Motoshima, Chang Wu, Amany Sayed Mawas, Yorifumi Satou, Yuichiro Arima, Hisashi Hasumi, Ryosuke Jikuya, Kazuhide Makiyama, Yuichi Oike, Yasuhito Tanaka, Masaya Baba, Tomomi Kamba
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Current Issues in Molecular Biology
Subjects:
TFE3-RCC
TFE3 fusion
<i>ARID2</i>
ERBB3
Online Access:https://www.mdpi.com/1467-3045/46/12/817
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