Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans

Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans

ABSTRACT Fungal sexual reproduction is controlled by the mating-type (MAT) locus. In contrast to a majority of species in the phylum Basidiomycota that have tetrapolar mating-type systems, the opportunistic human pathogen Cryptococcus neoformans employs a bipolar mating-type system, with two mating...

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Main Authors: Zhuyun Bian, Ziyan Xu, Anushka Peer, Yeseul Choi, Shelby J. Priest, Konstantina Akritidou, Ananya Dasgupta, Tim A. Dahlmann, Ulrich Kück, Minou Nowrousian, Matthew S. Sachs, Sheng Sun, Joseph Heitman
Format: Article
Language:English
Published: American Society for Microbiology 2025-04-01
Series:mBio
Subjects:
mating-type locus
Cryptococcus neoformans
molecular genetics
essential genes
pathogenicity
Online Access:https://journals.asm.org/doi/10.1128/mbio.00223-25
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