Rare variants in the endocytic pathway are associated with Alzheimer's disease, its related phenotypes, and functional consequences.
Late-onset Alzheimer's disease (LOAD) is the most common type of dementia causing irreversible brain damage to the elderly and presents a major public health challenge. Clinical research and genome-wide association studies have suggested a potential contribution of the endocytic pathway to AD,...
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| Main Authors: | Lingyu Zhan, Jiajin Li, Brandon Jew, Jae Hoon Sul |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-09-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009772&type=printable |
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