Reversible Oxygenation of α-Amino Acid–Cobalt(II) Complexes
We systematically investigated the reversibility, time lapse, and oxygenation-deoxygenation properties of 15 natural α-amino acid–Co(II) complexes through UV-vis spectrophotometer, polarographic oxygen electrode, and DFT calculations, respectively, to explore the relationship between the coordinatin...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2016/3585781 |
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| author | Xincun Zhang Fan Yue Hui Li Yan Huang Yi Zhang Hongmei Wen Jide Wang |
| author_facet | Xincun Zhang Fan Yue Hui Li Yan Huang Yi Zhang Hongmei Wen Jide Wang |
| author_sort | Xincun Zhang |
| collection | DOAJ |
| description | We systematically investigated the reversibility, time lapse, and oxygenation-deoxygenation properties of 15 natural α-amino acid–Co(II) complexes through UV-vis spectrophotometer, polarographic oxygen electrode, and DFT calculations, respectively, to explore the relationship between the coordinating structure and reversible oxygenation of α-amino acid–Co(II) complexes. Results revealed that the α-amino acid structure plays a key role in the reversible oxygenation properties of these complexes. The specific configuration of the α-amino acid group affects the eg1 electron of Co(II) transfer to the π⁎ orbit of O2; this phenomenon also favors the reversible formation and dissociation of Co–O2 bond when O2 coordinates with Co(II) complexes. Therefore, the co-coordination of amino and carboxyl groups is a determinant of Co complexes to absorb O2 reversibly. The group adjacent to the α-amino acid unit evidently influences the dioxygen affinity and antioxidation ability of the complexes. The presence of amino (or imino) and hydroxy groups adjacent to the α-amino acid group increases the oxygenation-deoxygenation rate and the number of reversible cycles. Our findings demonstrate a new mechanism to develop reversible oxygenation complexes and to reveal the oxygenation of oxygen carriers. |
| format | Article |
| id | doaj-art-98c07661b8134ee181d20164e401c96f |
| institution | Kabale University |
| issn | 1565-3633 1687-479X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioinorganic Chemistry and Applications |
| spelling | doaj-art-98c07661b8134ee181d20164e401c96f2025-02-03T06:01:32ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2016-01-01201610.1155/2016/35857813585781Reversible Oxygenation of α-Amino Acid–Cobalt(II) ComplexesXincun Zhang0Fan Yue1Hui Li2Yan Huang3Yi Zhang4Hongmei Wen5Jide Wang6Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education and Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi, Xinjiang 830046, ChinaKey Laboratory of Oil and Gas Fine Chemicals, Ministry of Education and Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi, Xinjiang 830046, ChinaKey Laboratory of Oil and Gas Fine Chemicals, Ministry of Education and Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi, Xinjiang 830046, ChinaKey Laboratory of Oil and Gas Fine Chemicals, Ministry of Education and Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi, Xinjiang 830046, ChinaCollege of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan 410083, ChinaKey Laboratory of Oil and Gas Fine Chemicals, Ministry of Education and Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi, Xinjiang 830046, ChinaKey Laboratory of Oil and Gas Fine Chemicals, Ministry of Education and Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi, Xinjiang 830046, ChinaWe systematically investigated the reversibility, time lapse, and oxygenation-deoxygenation properties of 15 natural α-amino acid–Co(II) complexes through UV-vis spectrophotometer, polarographic oxygen electrode, and DFT calculations, respectively, to explore the relationship between the coordinating structure and reversible oxygenation of α-amino acid–Co(II) complexes. Results revealed that the α-amino acid structure plays a key role in the reversible oxygenation properties of these complexes. The specific configuration of the α-amino acid group affects the eg1 electron of Co(II) transfer to the π⁎ orbit of O2; this phenomenon also favors the reversible formation and dissociation of Co–O2 bond when O2 coordinates with Co(II) complexes. Therefore, the co-coordination of amino and carboxyl groups is a determinant of Co complexes to absorb O2 reversibly. The group adjacent to the α-amino acid unit evidently influences the dioxygen affinity and antioxidation ability of the complexes. The presence of amino (or imino) and hydroxy groups adjacent to the α-amino acid group increases the oxygenation-deoxygenation rate and the number of reversible cycles. Our findings demonstrate a new mechanism to develop reversible oxygenation complexes and to reveal the oxygenation of oxygen carriers.http://dx.doi.org/10.1155/2016/3585781 |
| spellingShingle | Xincun Zhang Fan Yue Hui Li Yan Huang Yi Zhang Hongmei Wen Jide Wang Reversible Oxygenation of α-Amino Acid–Cobalt(II) Complexes Bioinorganic Chemistry and Applications |
| title | Reversible Oxygenation of α-Amino Acid–Cobalt(II) Complexes |
| title_full | Reversible Oxygenation of α-Amino Acid–Cobalt(II) Complexes |
| title_fullStr | Reversible Oxygenation of α-Amino Acid–Cobalt(II) Complexes |
| title_full_unstemmed | Reversible Oxygenation of α-Amino Acid–Cobalt(II) Complexes |
| title_short | Reversible Oxygenation of α-Amino Acid–Cobalt(II) Complexes |
| title_sort | reversible oxygenation of α amino acid cobalt ii complexes |
| url | http://dx.doi.org/10.1155/2016/3585781 |
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