Immunosuppressive tumor microenvironment in pancreatic cancer: mechanisms and therapeutic targets

Pancreatic cancer is projected to become the second leading cause of cancer−related death by 2030. Conventional interventions including surgery, radiotherapy, and chemotherapy provide only modest survival benefits, underscoring an urgent need for more effective therapies. Although immunotherapy has...

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Bibliographic Details
Main Authors: Da Pan, Xinyue Li, Xiao Qiao, Qiqi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1582305/full
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