Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice.

Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice.

<h4>Background and aims</h4>Neuropilin 1 (NRP1) is a non-tyrosine kinase receptor for vascular endothelial growth factor (VEGF) and class 3 semaphorins, playing a role in angiogenesis and neuronal axon guidance, respectively. NRP1 is expressed in smooth muscle cells (SMC) but the functio...

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Main Authors: Maiko Yamaji, Marwa Mahmoud, Ian M Evans, Ian C Zachary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115563
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