Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2
ABSTRACT Objective: To correlate disease duration in spinocerebellar ataxia type 2 (SCA2) with disease severity, balance and functionality. Method: Sixteen SCA2 patients were analyzed for: disease duration, disease severity (SARA score), balance (Berg balance scale score) and functionality (FIM an...
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| Series: | Arquivos de Neuro-Psiquiatria |
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| author | Thiago R. Padilha Amarante Sibele Y. M. Takeda Hélio A. G. Teive Marise Bueno Zonta |
| author_facet | Thiago R. Padilha Amarante Sibele Y. M. Takeda Hélio A. G. Teive Marise Bueno Zonta |
| author_sort | Thiago R. Padilha Amarante |
| collection | DOAJ |
| description | ABSTRACT Objective: To correlate disease duration in spinocerebellar ataxia type 2 (SCA2) with disease severity, balance and functionality. Method: Sixteen SCA2 patients were analyzed for: disease duration, disease severity (SARA score), balance (Berg balance scale score) and functionality (FIM and Lawton scores). Results: Greater severity was correlated with worse functionality (Lawton: r = −0.0561, FIM: r = −0.6402) and balance (r = −0.7188). Longer disease duration was correlated with greater severity (p = 0.0002) and reduced functionality (FIM: p = 0.005; Lawton: p = 0.0402) and balance (p = 0.0036). A year increase in disease duration corresponded to a 0.8-point increase on the SARA scale, a 1.38-point decrease in FIM score, a 2.30-point decrease on the Berg balance scale and a 0.45-point decrease on the Lawton scale. Conclusion: Longer disease duration in this series of SCA2 patients was correlated with greater disease severity, worse balance and greater functional dependency. |
| format | Article |
| id | doaj-art-98b171caf99f48a9afbe6dda6f39c30d |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-98b171caf99f48a9afbe6dda6f39c30d2025-08-20T03:18:56ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-4227751177377710.1590/0004-282x20170146S0004-282X2017001100773Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2Thiago R. Padilha AmaranteSibele Y. M. TakedaHélio A. G. TeiveMarise Bueno ZontaABSTRACT Objective: To correlate disease duration in spinocerebellar ataxia type 2 (SCA2) with disease severity, balance and functionality. Method: Sixteen SCA2 patients were analyzed for: disease duration, disease severity (SARA score), balance (Berg balance scale score) and functionality (FIM and Lawton scores). Results: Greater severity was correlated with worse functionality (Lawton: r = −0.0561, FIM: r = −0.6402) and balance (r = −0.7188). Longer disease duration was correlated with greater severity (p = 0.0002) and reduced functionality (FIM: p = 0.005; Lawton: p = 0.0402) and balance (p = 0.0036). A year increase in disease duration corresponded to a 0.8-point increase on the SARA scale, a 1.38-point decrease in FIM score, a 2.30-point decrease on the Berg balance scale and a 0.45-point decrease on the Lawton scale. Conclusion: Longer disease duration in this series of SCA2 patients was correlated with greater disease severity, worse balance and greater functional dependency.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017001100773&lng=en&tlng=enspinocerebellar ataxiasseverity of illness indexpostural balance |
| spellingShingle | Thiago R. Padilha Amarante Sibele Y. M. Takeda Hélio A. G. Teive Marise Bueno Zonta Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2 Arquivos de Neuro-Psiquiatria spinocerebellar ataxias severity of illness index postural balance |
| title | Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2 |
| title_full | Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2 |
| title_fullStr | Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2 |
| title_full_unstemmed | Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2 |
| title_short | Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2 |
| title_sort | impact of disease duration on functional status of patients with spinocerebellar ataxia type 2 |
| topic | spinocerebellar ataxias severity of illness index postural balance |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017001100773&lng=en&tlng=en |
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