Age-related changes in DNA methylation in a sample of elderly Brazilians

Age-related changes in DNA methylation in a sample of elderly Brazilians

Abstract Background Age-related changes in DNA methylation (DNAm) play a critical role in regulating gene expression. However, most epigenome-wide association studies have predominantly focused on individuals of European descent. This study aims to characterize longitudinal changes in DNAm patterns...

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Bibliographic Details
Main Authors: Hayley Welsh, Caio M. P. F. Batalha, Weili Li, Nadja C. Souza-Pinto, Yeda A. O. Duarte, Michel S. Naslavsky, Esteban J. Parra
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Illumina EPIC array
Molecular aging
Longitudinal study
Online Access:https://doi.org/10.1186/s13148-025-01821-3
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