Bayesian fine-mapping and Mendelian randomization leveraging expression quantitative trait loci reveal novel candidate causal genes for body conformation traits in cattle

Bayesian fine-mapping and Mendelian randomization leveraging expression quantitative trait loci reveal novel candidate causal genes for body conformation traits in cattle

ABSTRACT: Cattle body size measurements constitute the conformation traits that facilitate their production, fertility, and longevity status. Prioritizing functional variants and causal genes of conformation traits is essential for understanding their genetic basis. In this study, we conducted singl...

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Bibliographic Details
Main Authors: Jun Teng, Chongwei Duan, Xinyi Zhang, Zhujun Chen, Chao Ning, Rongling Li, Yundong Gao, Hongding Gao, Huiming Liu, Jianbin Li, Xiao Wang, Qin Zhang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Dairy Science
Subjects:
GWAS
Bayesian fine-mapping
Mendelian randomization
body conformation traits
cattle
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030225003649
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