Insights from precision-cut lung slices—investigating mechanisms and therapeutics for pulmonary hypertension

Abstract Precision-cut lung slices (PCLS) are gaining traction as a versatile ex vivo tool to study mechanisms and treatments for lung diseases. This preparation, in which the major structural elements of the native lung are preserved, bridges the gap between cell and in vivo models allowing researc...

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Bibliographic Details
Main Authors: William R. Studley, Emma Lamanna, Claudia A. Nold-Petry, Cheng Xue Qin, Jane E. Bourke
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Respiratory Research
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Online Access:https://doi.org/10.1186/s12931-025-03290-x
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