Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and Hyperopia

Background. To study the effect of cycloplegia on ocular parameters in children with myopia and hyperopia. Methods. Forty-two myopia and forty-four hyperopia eyes in children between 5 and 10 years of age were included. Measurements were taken before and after cycloplegia using 1% atropine sulfate o...

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Main Authors: Guangzhi Qu, Bingfeng Wang, Saisai Ding, Xiaocui Liu, Lei Gao, Xuli Wang
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2023/9003942
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author Guangzhi Qu
Bingfeng Wang
Saisai Ding
Xiaocui Liu
Lei Gao
Xuli Wang
author_facet Guangzhi Qu
Bingfeng Wang
Saisai Ding
Xiaocui Liu
Lei Gao
Xuli Wang
author_sort Guangzhi Qu
collection DOAJ
description Background. To study the effect of cycloplegia on ocular parameters in children with myopia and hyperopia. Methods. Forty-two myopia and forty-four hyperopia eyes in children between 5 and 10 years of age were included. Measurements were taken before and after cycloplegia using 1% atropine sulfate ointment. The ocular parameters included central corneal thickness (CCT), corneal curvature (CC), anterior chamber depth (ACD), pupil diameter (PD), axial length (AL), and central retinal thickness (CRT). Results. There was no significant difference in CCT, CC, and CRT between the two groups without cycloplegia, but the ACD of the myopia (3.64 ± 0.28 mm) group was significantly higher than that of hyperopia (3.40 ± 0.24 mm; t = −4.522; P<0.0001). The average PD of the myopia (4.85 ± 0.87 mm) group was significantly smaller than that of the hyperopia group (5.47 ± 1.15 mm; t = 2.903; P<0.0046). The average AL of myopia (24.25 ± 0.77 mm) was significantly higher than that of hyperopia (21.73 ± 1.24 mm; t = 12.084; P<0.0001). However, it was found that the average PD of myopia (7.68 ± 0.51 mm) was significantly larger than that of hyperopia (7.41 ± 0.57 mm; t = 2.364; P=0.0202) under cycloplegia. As for the changes in refractive factors before and after cycloplegia, deepened ACD and enlarged PD were noted in both the groups after cycloplegia. Conclusions. Cycloplegia not only affects ACD and PD but also leads to the reversal of PD differences between the two groups. Cycloplegia effects enabled us to study changes in all known ocular parameters in a short period.
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spelling doaj-art-9897c83a37b345ca8e97d6611ffad3f42025-08-20T03:37:22ZengWileyJournal of Ophthalmology2090-00582023-01-01202310.1155/2023/9003942Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and HyperopiaGuangzhi Qu0Bingfeng Wang1Saisai Ding2Xiaocui Liu3Lei Gao4Xuli Wang5Department of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyBackground. To study the effect of cycloplegia on ocular parameters in children with myopia and hyperopia. Methods. Forty-two myopia and forty-four hyperopia eyes in children between 5 and 10 years of age were included. Measurements were taken before and after cycloplegia using 1% atropine sulfate ointment. The ocular parameters included central corneal thickness (CCT), corneal curvature (CC), anterior chamber depth (ACD), pupil diameter (PD), axial length (AL), and central retinal thickness (CRT). Results. There was no significant difference in CCT, CC, and CRT between the two groups without cycloplegia, but the ACD of the myopia (3.64 ± 0.28 mm) group was significantly higher than that of hyperopia (3.40 ± 0.24 mm; t = −4.522; P<0.0001). The average PD of the myopia (4.85 ± 0.87 mm) group was significantly smaller than that of the hyperopia group (5.47 ± 1.15 mm; t = 2.903; P<0.0046). The average AL of myopia (24.25 ± 0.77 mm) was significantly higher than that of hyperopia (21.73 ± 1.24 mm; t = 12.084; P<0.0001). However, it was found that the average PD of myopia (7.68 ± 0.51 mm) was significantly larger than that of hyperopia (7.41 ± 0.57 mm; t = 2.364; P=0.0202) under cycloplegia. As for the changes in refractive factors before and after cycloplegia, deepened ACD and enlarged PD were noted in both the groups after cycloplegia. Conclusions. Cycloplegia not only affects ACD and PD but also leads to the reversal of PD differences between the two groups. Cycloplegia effects enabled us to study changes in all known ocular parameters in a short period.http://dx.doi.org/10.1155/2023/9003942
spellingShingle Guangzhi Qu
Bingfeng Wang
Saisai Ding
Xiaocui Liu
Lei Gao
Xuli Wang
Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and Hyperopia
Journal of Ophthalmology
title Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and Hyperopia
title_full Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and Hyperopia
title_fullStr Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and Hyperopia
title_full_unstemmed Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and Hyperopia
title_short Effects of Cycloplegic Agents on Ocular Parameters in Children with Myopia and Hyperopia
title_sort effects of cycloplegic agents on ocular parameters in children with myopia and hyperopia
url http://dx.doi.org/10.1155/2023/9003942
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