Association between Serum Phosphorus Levels and Diabetic Retinopathy: A Cross-Sectional Study
Background and Aims. The aim of this study was to investigate the association between serum phosphate levels and diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Methods and Results. The study sample consisted of 1657 T2DM patients hospitalized between 2017 and 2019. Patie...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2024/3830246 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849403091044007936 |
|---|---|
| author | Jintao Chen Chuanfeng Liu Cunwei Sun Jia Zeng Jingwei Chi Kui Che Yangang Wang |
| author_facet | Jintao Chen Chuanfeng Liu Cunwei Sun Jia Zeng Jingwei Chi Kui Che Yangang Wang |
| author_sort | Jintao Chen |
| collection | DOAJ |
| description | Background and Aims. The aim of this study was to investigate the association between serum phosphate levels and diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Methods and Results. The study sample consisted of 1657 T2DM patients hospitalized between 2017 and 2019. Patients were categorized into quartiles based on their serum phosphate levels (Q1–Q4). An increasing trend in the prevalence of DR was observed across these quartiles. Subsequently, logistic regression analysis was employed to adjust for potential confounders, such as gender, age, BMI, and duration of diabetes, and to evaluate the odds ratios (ORs) associated with these quartiles. The prevalence of DR showed an increasing trend with elevated serum phosphate levels. Logistic regression further confirmed that serum phosphate levels remain an independent risk factor for DR. Conclusion. Elevated serum phosphate levels are closely associated with the prevalence of DR in hospitalized T2DM patients. Further studies are needed to establish causality. This trial is registered with chiCTR2000032374. |
| format | Article |
| id | doaj-art-98954400d4b24914b4a25e0e4e45d338 |
| institution | Kabale University |
| issn | 1687-8345 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-98954400d4b24914b4a25e0e4e45d3382025-08-20T03:37:22ZengWileyInternational Journal of Endocrinology1687-83452024-01-01202410.1155/2024/3830246Association between Serum Phosphorus Levels and Diabetic Retinopathy: A Cross-Sectional StudyJintao Chen0Chuanfeng Liu1Cunwei Sun2Jia Zeng3Jingwei Chi4Kui Che5Yangang Wang6Department of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyDepartment of EndocrinologyBackground and Aims. The aim of this study was to investigate the association between serum phosphate levels and diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Methods and Results. The study sample consisted of 1657 T2DM patients hospitalized between 2017 and 2019. Patients were categorized into quartiles based on their serum phosphate levels (Q1–Q4). An increasing trend in the prevalence of DR was observed across these quartiles. Subsequently, logistic regression analysis was employed to adjust for potential confounders, such as gender, age, BMI, and duration of diabetes, and to evaluate the odds ratios (ORs) associated with these quartiles. The prevalence of DR showed an increasing trend with elevated serum phosphate levels. Logistic regression further confirmed that serum phosphate levels remain an independent risk factor for DR. Conclusion. Elevated serum phosphate levels are closely associated with the prevalence of DR in hospitalized T2DM patients. Further studies are needed to establish causality. This trial is registered with chiCTR2000032374.http://dx.doi.org/10.1155/2024/3830246 |
| spellingShingle | Jintao Chen Chuanfeng Liu Cunwei Sun Jia Zeng Jingwei Chi Kui Che Yangang Wang Association between Serum Phosphorus Levels and Diabetic Retinopathy: A Cross-Sectional Study International Journal of Endocrinology |
| title | Association between Serum Phosphorus Levels and Diabetic Retinopathy: A Cross-Sectional Study |
| title_full | Association between Serum Phosphorus Levels and Diabetic Retinopathy: A Cross-Sectional Study |
| title_fullStr | Association between Serum Phosphorus Levels and Diabetic Retinopathy: A Cross-Sectional Study |
| title_full_unstemmed | Association between Serum Phosphorus Levels and Diabetic Retinopathy: A Cross-Sectional Study |
| title_short | Association between Serum Phosphorus Levels and Diabetic Retinopathy: A Cross-Sectional Study |
| title_sort | association between serum phosphorus levels and diabetic retinopathy a cross sectional study |
| url | http://dx.doi.org/10.1155/2024/3830246 |
| work_keys_str_mv | AT jintaochen associationbetweenserumphosphoruslevelsanddiabeticretinopathyacrosssectionalstudy AT chuanfengliu associationbetweenserumphosphoruslevelsanddiabeticretinopathyacrosssectionalstudy AT cunweisun associationbetweenserumphosphoruslevelsanddiabeticretinopathyacrosssectionalstudy AT jiazeng associationbetweenserumphosphoruslevelsanddiabeticretinopathyacrosssectionalstudy AT jingweichi associationbetweenserumphosphoruslevelsanddiabeticretinopathyacrosssectionalstudy AT kuiche associationbetweenserumphosphoruslevelsanddiabeticretinopathyacrosssectionalstudy AT yangangwang associationbetweenserumphosphoruslevelsanddiabeticretinopathyacrosssectionalstudy |