Characterisation of macrophages in healthy and diseased livers in mice: identification of necrotic lesion-associated macrophages

Background Healthy livers contain a large number of resident macrophages named Kupffer cells (KCs), which are partially replaced by infiltrating monocyte-derived macrophages (MoMFs) during acute or chronic liver injury. Despite extensive research, understanding macrophage heterogeneity, spatial dist...

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Bibliographic Details
Main Authors: Yang Wang, Dechun Feng, Bin Gao, Bryan Mackowiak, Yukun Guan, Luca Maccioni
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:eGastroenterology
Online Access:https://egastroenterology.bmj.com/content/3/2/e100189.full
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