BESPOKE study protocol: a multicentre, prospective observational study to evaluate the impact of circulating tumour DNA guided therapy on patients with colorectal cancer

BESPOKE study protocol: a multicentre, prospective observational study to evaluate the impact of circulating tumour DNA guided therapy on patients with colorectal cancer

Introduction Colorectal cancer (CRC) is a highly prevalent disease, wherein, ~30%–40% of patients with CRC relapse postresection. In some patients with CRC, adjuvant chemotherapy can help delay recurrence or be curative. However, current biomarkers show limited clinical utility in determining if/whe...

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Bibliographic Details
Main Authors: Scott Kopetz, Axel Grothey, Shifra Krinshpun, Meenakshi Malhotra, Paul Billings, Angel Rodriguez, Alexey Aleshin, Sarah Sawyer, Michelle Munro, Pashtoon Murtaza Kasi, Jessica Guilford, Sascha Ellers, Jacob Wulff, Nicole Hook, Allyson Koyen Malashevich, Solomon Moshkevich
Format: Article
Language:English
Published: BMJ Publishing Group 2021-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/9/e047831.full
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