Correction of cyclophosphan hepatotoxicity by water-soluble polysaccharides from Tussilago farfara and Acorus calamus

In experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclo...

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Main Authors: Ye. A. Safonova, K. A. Lopatina, T. V. Vetoshkina, A. M. Guriyev, T. G. Razina, Ye. P. Zuyeva
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2011-02-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/1318
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Summary:In experiments on rats with Walker-256 carcinosarcoma the ability of water-soluble polysaccharides from Tussilago farfara and Acorus calamus influence on efficiency antineoplastic therapy and hepatotoxicity investigated. Polysaccharides reduce a level of liver enzymes in blood serum of rats at cyclophosphamide damaged liver, as well as increase the antimetastatic effect of cytostatics. Water-soluble polysaccharides from Acorus calamus restore most efficiently biochemical disturbances at cyclophosphamide intoxication.
ISSN:1682-0363
1819-3684