Subclinical Cardiac Involvement in Asymptomatic ATTR Mutation Carriers: Insights from Cardiac MRI, Myocardial Strain, and Mapping Techniques

Subclinical Cardiac Involvement in Asymptomatic ATTR Mutation Carriers: Insights from Cardiac MRI, Myocardial Strain, and Mapping Techniques

Transthyretin cardiac amyloidosis (ATTR-CA) leads to myocardial infiltration, affecting prognosis and survival. Diagnosing early-stage ATTR-CA remains challenging due to its subtle manifestations. This study investigates subclinical myocardial alterations in asymptomatic ATTR mutation carriers (ATTR...

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Bibliographic Details
Main Authors: Luca Conia, Daria Filatova, Giacomo Pambianchi, Livia Marchitelli, Giulia Cundari, Giuseppe Stancanelli, Maria Alfarano, Giulia Marchionni, Cristina Chimenti, Carlo Catalano, Nicola Galea
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
amyloidosis
cardiac magnetic resonance
transthyretin
T1 mapping
ECV
myocardial strain
Online Access:https://www.mdpi.com/2308-3425/12/5/172
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