IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury

IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury

PurposeAcute kidney injury (AKI) secondary to Rhabdomyolysis syndrome represents a life-threatening complication, characterized by notably high incidence and mortality rates. The role of cellular senescence in the progression of AKI has increasingly garnered attention in recent years. Our previous r...

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Bibliographic Details
Main Authors: Hongshuang Su, Xiaoxi Lin, Ayinuer Paredong, Congcong Yao, Yan Zhang, Mengke Geng, Yuqian Guan, Lichao Gong, Feng Jiang, Qi Lv, Songtao Shou, Heng Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
rhabdomyolysis-induced acute kidney injury
IL-6
SERPINE1
GATA2
cellular senescence
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1538526/full
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