Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes
We report a case presenting with recurrent episodes of severe hypothermia preceding the diagnosis of Hodgkin lymphoma. The episodes of hypothermia were accompanied by other symptoms of autonomic dysfunction, mainly hypotension, which could be caused by autonomic neuropathy as part of a paraneoplasti...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2018/3726593 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832563649575649280 |
|---|---|
| author | Jonas Juul Hansen Hans Beier Ommen Lars Christian Gormsen Francesco Annibale d’Amore Peter Martin Hjørnet Kamper |
| author_facet | Jonas Juul Hansen Hans Beier Ommen Lars Christian Gormsen Francesco Annibale d’Amore Peter Martin Hjørnet Kamper |
| author_sort | Jonas Juul Hansen |
| collection | DOAJ |
| description | We report a case presenting with recurrent episodes of severe hypothermia preceding the diagnosis of Hodgkin lymphoma. The episodes of hypothermia were accompanied by other symptoms of autonomic dysfunction, mainly hypotension, which could be caused by autonomic neuropathy as part of a paraneoplastic syndrome. In comparison with previous reports describing an association between the presence of hypothermia and an adverse outcome, the present patient has responded well to lymphoma-specific treatment and is currently in an ongoing complete remission. Due to the peculiar cyclic pattern of the hypothermic episodes presented in this case, we hypothesize whether intermittent release of disease-related chemo- and cytokines could be a plausible pathogenetic explanation. |
| format | Article |
| id | doaj-art-986fc1ec483c4d9cb5857125fd2f8128 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-986fc1ec483c4d9cb5857125fd2f81282025-02-03T01:12:57ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/37265933726593Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic EpisodesJonas Juul Hansen0Hans Beier Ommen1Lars Christian Gormsen2Francesco Annibale d’Amore3Peter Martin Hjørnet Kamper4Department of Hematology, Aarhus University Hospital, Tage-Hansens Gade 2, DK-8000 Aarhus, DenmarkDepartment of Hematology, Aarhus University Hospital, Tage-Hansens Gade 2, DK-8000 Aarhus, DenmarkDepartment of Nuclear Medicine and PET Center, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus, DenmarkDepartment of Hematology, Aarhus University Hospital, Tage-Hansens Gade 2, DK-8000 Aarhus, DenmarkDepartment of Hematology, Aarhus University Hospital, Tage-Hansens Gade 2, DK-8000 Aarhus, DenmarkWe report a case presenting with recurrent episodes of severe hypothermia preceding the diagnosis of Hodgkin lymphoma. The episodes of hypothermia were accompanied by other symptoms of autonomic dysfunction, mainly hypotension, which could be caused by autonomic neuropathy as part of a paraneoplastic syndrome. In comparison with previous reports describing an association between the presence of hypothermia and an adverse outcome, the present patient has responded well to lymphoma-specific treatment and is currently in an ongoing complete remission. Due to the peculiar cyclic pattern of the hypothermic episodes presented in this case, we hypothesize whether intermittent release of disease-related chemo- and cytokines could be a plausible pathogenetic explanation.http://dx.doi.org/10.1155/2018/3726593 |
| spellingShingle | Jonas Juul Hansen Hans Beier Ommen Lars Christian Gormsen Francesco Annibale d’Amore Peter Martin Hjørnet Kamper Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes Case Reports in Hematology |
| title | Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes |
| title_full | Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes |
| title_fullStr | Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes |
| title_full_unstemmed | Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes |
| title_short | Classical Hodgkin Lymphoma Presenting with Severe, Recurrent Hypothermic Episodes |
| title_sort | classical hodgkin lymphoma presenting with severe recurrent hypothermic episodes |
| url | http://dx.doi.org/10.1155/2018/3726593 |
| work_keys_str_mv | AT jonasjuulhansen classicalhodgkinlymphomapresentingwithsevererecurrenthypothermicepisodes AT hansbeierommen classicalhodgkinlymphomapresentingwithsevererecurrenthypothermicepisodes AT larschristiangormsen classicalhodgkinlymphomapresentingwithsevererecurrenthypothermicepisodes AT francescoannibaledamore classicalhodgkinlymphomapresentingwithsevererecurrenthypothermicepisodes AT petermartinhjørnetkamper classicalhodgkinlymphomapresentingwithsevererecurrenthypothermicepisodes |