Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices
Background and Aim. The third-generation capsule endoscopy (SB3) was shown to have better image resolution than that of SB2. The aim of this study was to compare SB2 and SB3 regarding detectability of esophageal varices (EVs). Methods. Seventy-six consecutive liver cirrhosis patients (42 men; mean a...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/9671327 |
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| author | Sayoko Kunihara Shiro Oka Shinji Tanaka Ichiro Otani Atsushi Igawa Yuko Nagaoki Hiroshi Aikata Kazuaki Chayama |
| author_facet | Sayoko Kunihara Shiro Oka Shinji Tanaka Ichiro Otani Atsushi Igawa Yuko Nagaoki Hiroshi Aikata Kazuaki Chayama |
| author_sort | Sayoko Kunihara |
| collection | DOAJ |
| description | Background and Aim. The third-generation capsule endoscopy (SB3) was shown to have better image resolution than that of SB2. The aim of this study was to compare SB2 and SB3 regarding detectability of esophageal varices (EVs). Methods. Seventy-six consecutive liver cirrhosis patients (42 men; mean age: 67 years) received SB3, and 99 (58 men; mean age, 67 years old) received SB2. All patients underwent esophagogastroduodenoscopy within 1 month prior to capsule endoscopy as gold standard for diagnosis. The diagnosis using SB3 and SB2 for EVs was evaluated regarding form (F0–F3), location (Ls, Lm, and Li), and the red color (RC) sign of EVs. Results. SB2 and SB3 did not significantly differ on overall diagnostic rates for EV. Sensitivity, specificity, positive predictive value, and negative predictive value of SB2/SB3 for EV diagnosis were, respectively, 65%/81%, 100%/100%, 100%/100%, and 70%/62%. However, the diagnostic rates for EV form F1 were 81% using SB3 and 52% using SB2 (P=0.009). Further, the diagnostic rates for Ls/Lm varices were 79% using SB3 and 81% using SB2, and, for Li, varices were 84% using SB3 and 52% using SB2 (P=0.02). Conclusion. SB3 significantly improved the detectability of EVs compared with SB2. |
| format | Article |
| id | doaj-art-985f582298644b64813406c506055777 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-985f582298644b64813406c5060557772025-02-03T06:13:53ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/96713279671327Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal VaricesSayoko Kunihara0Shiro Oka1Shinji Tanaka2Ichiro Otani3Atsushi Igawa4Yuko Nagaoki5Hiroshi Aikata6Kazuaki Chayama7Department of Gastroenterology and Metabolism, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JapanDepartment of Gastroenterology and Metabolism, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JapanDepartment of Endoscopy and Medicine, Hiroshima University Hospital, Hiroshima, JapanDepartment of Gastroenterology and Metabolism, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JapanDepartment of Gastroenterology and Metabolism, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JapanDepartment of Gastroenterology and Metabolism, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JapanDepartment of Gastroenterology and Metabolism, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JapanDepartment of Gastroenterology and Metabolism, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JapanBackground and Aim. The third-generation capsule endoscopy (SB3) was shown to have better image resolution than that of SB2. The aim of this study was to compare SB2 and SB3 regarding detectability of esophageal varices (EVs). Methods. Seventy-six consecutive liver cirrhosis patients (42 men; mean age: 67 years) received SB3, and 99 (58 men; mean age, 67 years old) received SB2. All patients underwent esophagogastroduodenoscopy within 1 month prior to capsule endoscopy as gold standard for diagnosis. The diagnosis using SB3 and SB2 for EVs was evaluated regarding form (F0–F3), location (Ls, Lm, and Li), and the red color (RC) sign of EVs. Results. SB2 and SB3 did not significantly differ on overall diagnostic rates for EV. Sensitivity, specificity, positive predictive value, and negative predictive value of SB2/SB3 for EV diagnosis were, respectively, 65%/81%, 100%/100%, 100%/100%, and 70%/62%. However, the diagnostic rates for EV form F1 were 81% using SB3 and 52% using SB2 (P=0.009). Further, the diagnostic rates for Ls/Lm varices were 79% using SB3 and 81% using SB2, and, for Li, varices were 84% using SB3 and 52% using SB2 (P=0.02). Conclusion. SB3 significantly improved the detectability of EVs compared with SB2.http://dx.doi.org/10.1155/2016/9671327 |
| spellingShingle | Sayoko Kunihara Shiro Oka Shinji Tanaka Ichiro Otani Atsushi Igawa Yuko Nagaoki Hiroshi Aikata Kazuaki Chayama Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices Gastroenterology Research and Practice |
| title | Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices |
| title_full | Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices |
| title_fullStr | Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices |
| title_full_unstemmed | Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices |
| title_short | Third-Generation Capsule Endoscopy Outperforms Second-Generation Based on the Detectability of Esophageal Varices |
| title_sort | third generation capsule endoscopy outperforms second generation based on the detectability of esophageal varices |
| url | http://dx.doi.org/10.1155/2016/9671327 |
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