THE PARAMETERS OF THE OXYGEN STATUS IN THE ASSESSMENT OF PROGNOSIS OF A HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS PRETERM NEONATAL INFANTS
Objective: to estimate the significance of capillary blood oxygen parameters for the prognosis of longstanding hemodynamically significant patent ductus arteriosus (HSPDA) in extremely low birthweight (ELBW) neonates. Subjects and methods. On day 8 of their life, two groups of ELBW newborn infants w...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2015-05-01
|
| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1454 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849242866599067648 |
|---|---|
| author | M. V. Perestoronina O. V. Korpacheva S. V. Palyanov V. T. Dolgikh |
| author_facet | M. V. Perestoronina O. V. Korpacheva S. V. Palyanov V. T. Dolgikh |
| author_sort | M. V. Perestoronina |
| collection | DOAJ |
| description | Objective: to estimate the significance of capillary blood oxygen parameters for the prognosis of longstanding hemodynamically significant patent ductus arteriosus (HSPDA) in extremely low birthweight (ELBW) neonates. Subjects and methods. On day 8 of their life, two groups of ELBW newborn infants with and without HSPDA were examined for capillary blood рН, рkО2, %SO2с, O2ct, АkDO2, and RIk, as well as mechanical ventilation (MV) parameters (Pip, MAP, and FiO2). Comparison of two independent samples used nonparametric statistical tests: MannWhitney test, Wald Wolfowitz test, and Kolmogorov-Smirnov test. A logistic regression analysis was used to assess the relationship between the examined parameters and the presence or absence of HSPDA. ROC curves were constructed, by choosing the cut-off point, to estimate the predictive power of the model developed using logistic regression. Results. The developed model has high sensitivity and high specificity (84,6 and 97% respectively). The logistic regression equation takes the form: -0.479•О2сt+0.708•Pip-6.823. Conclusion. Capillary blood oxygen parameters proved suitable for predicting the duration of HSPDA functioning. The resultant good predictive power of the model developed for day 8 of life points to the fact that this period is critical from the viewpoint of resolution of respiratory distress syndrome or development of bronchopulmonary dysplasia, which is crucially significant for MV duration and further prediction. HSPDA is one of the most important factors contributing to the development of bronchopulmonary dysplasia in ELBW neonatal infants. |
| format | Article |
| id | doaj-art-9859dc24e8fc4c0598ba8b7ef2aec4e1 |
| institution | Kabale University |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2015-05-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-9859dc24e8fc4c0598ba8b7ef2aec4e12025-08-20T03:59:40ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102015-05-01112354110.15360/1813-9779-2015-2-35-411446THE PARAMETERS OF THE OXYGEN STATUS IN THE ASSESSMENT OF PROGNOSIS OF A HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS PRETERM NEONATAL INFANTSM. V. Perestoronina0O. V. Korpacheva1S. V. Palyanov2V. T. Dolgikh3Omsk State Medical Academy, Ministry of Health of the Russian Federation, Omsk, Russia 12, Lenin St., Omsk 644099 City Clinical Perinatal Center, Omsk, Russia 69, Herzen St., Omsk 644007City Clinical Perinatal Center, Omsk, Russia 69, Herzen St., Omsk 644007Omsk State Medical Academy, Ministry of Health of the Russian Federation, Omsk, Russia 12, Lenin St., Omsk 644099 City Clinical Perinatal Center, Omsk, Russia 69, Herzen St., Omsk 644007Omsk State Medical Academy, Ministry of Health of the Russian Federation, Omsk, Russia 12, Lenin St., Omsk 644099Objective: to estimate the significance of capillary blood oxygen parameters for the prognosis of longstanding hemodynamically significant patent ductus arteriosus (HSPDA) in extremely low birthweight (ELBW) neonates. Subjects and methods. On day 8 of their life, two groups of ELBW newborn infants with and without HSPDA were examined for capillary blood рН, рkО2, %SO2с, O2ct, АkDO2, and RIk, as well as mechanical ventilation (MV) parameters (Pip, MAP, and FiO2). Comparison of two independent samples used nonparametric statistical tests: MannWhitney test, Wald Wolfowitz test, and Kolmogorov-Smirnov test. A logistic regression analysis was used to assess the relationship between the examined parameters and the presence or absence of HSPDA. ROC curves were constructed, by choosing the cut-off point, to estimate the predictive power of the model developed using logistic regression. Results. The developed model has high sensitivity and high specificity (84,6 and 97% respectively). The logistic regression equation takes the form: -0.479•О2сt+0.708•Pip-6.823. Conclusion. Capillary blood oxygen parameters proved suitable for predicting the duration of HSPDA functioning. The resultant good predictive power of the model developed for day 8 of life points to the fact that this period is critical from the viewpoint of resolution of respiratory distress syndrome or development of bronchopulmonary dysplasia, which is crucially significant for MV duration and further prediction. HSPDA is one of the most important factors contributing to the development of bronchopulmonary dysplasia in ELBW neonatal infants.https://www.reanimatology.com/rmt/article/view/1454oxygen parameterscapillary bloodprognosishemodynamically significant patent ductus arteriosusextremely low birthweight neonates |
| spellingShingle | M. V. Perestoronina O. V. Korpacheva S. V. Palyanov V. T. Dolgikh THE PARAMETERS OF THE OXYGEN STATUS IN THE ASSESSMENT OF PROGNOSIS OF A HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS PRETERM NEONATAL INFANTS Общая реаниматология oxygen parameters capillary blood prognosis hemodynamically significant patent ductus arteriosus extremely low birthweight neonates |
| title | THE PARAMETERS OF THE OXYGEN STATUS IN THE ASSESSMENT OF PROGNOSIS OF A HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS PRETERM NEONATAL INFANTS |
| title_full | THE PARAMETERS OF THE OXYGEN STATUS IN THE ASSESSMENT OF PROGNOSIS OF A HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS PRETERM NEONATAL INFANTS |
| title_fullStr | THE PARAMETERS OF THE OXYGEN STATUS IN THE ASSESSMENT OF PROGNOSIS OF A HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS PRETERM NEONATAL INFANTS |
| title_full_unstemmed | THE PARAMETERS OF THE OXYGEN STATUS IN THE ASSESSMENT OF PROGNOSIS OF A HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS PRETERM NEONATAL INFANTS |
| title_short | THE PARAMETERS OF THE OXYGEN STATUS IN THE ASSESSMENT OF PROGNOSIS OF A HEMODYNAMICALLY SIGNIFICANT PATENT DUCTUS ARTERIOSUS PRETERM NEONATAL INFANTS |
| title_sort | parameters of the oxygen status in the assessment of prognosis of a hemodynamically significant patent ductus arteriosus preterm neonatal infants |
| topic | oxygen parameters capillary blood prognosis hemodynamically significant patent ductus arteriosus extremely low birthweight neonates |
| url | https://www.reanimatology.com/rmt/article/view/1454 |
| work_keys_str_mv | AT mvperestoronina theparametersoftheoxygenstatusintheassessmentofprognosisofahemodynamicallysignificantpatentductusarteriosuspretermneonatalinfants AT ovkorpacheva theparametersoftheoxygenstatusintheassessmentofprognosisofahemodynamicallysignificantpatentductusarteriosuspretermneonatalinfants AT svpalyanov theparametersoftheoxygenstatusintheassessmentofprognosisofahemodynamicallysignificantpatentductusarteriosuspretermneonatalinfants AT vtdolgikh theparametersoftheoxygenstatusintheassessmentofprognosisofahemodynamicallysignificantpatentductusarteriosuspretermneonatalinfants AT mvperestoronina parametersoftheoxygenstatusintheassessmentofprognosisofahemodynamicallysignificantpatentductusarteriosuspretermneonatalinfants AT ovkorpacheva parametersoftheoxygenstatusintheassessmentofprognosisofahemodynamicallysignificantpatentductusarteriosuspretermneonatalinfants AT svpalyanov parametersoftheoxygenstatusintheassessmentofprognosisofahemodynamicallysignificantpatentductusarteriosuspretermneonatalinfants AT vtdolgikh parametersoftheoxygenstatusintheassessmentofprognosisofahemodynamicallysignificantpatentductusarteriosuspretermneonatalinfants |