FEATURES OF QUALITY ASSESSMENT AND STANDARDIZATION PROSPECTS OF FATTY OILS AND OIL EXTRACTS FOR PHARMACEUTICAL PURPOSES (REVIEW)
Today technologies stimulating growth and stabilization of new blood vessel, regulating trajectory of vascular growth are promising for the treatment of ischemia. These technologies represent a therapeutic angiogenesis. Its are essential in the rapidly developing regenerative medicine. In the presen...
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| Format: | Article |
| Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
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| Online Access: | https://www.pharmjournal.ru/jour/article/view/88 |
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| author | E. V. Semina P. S. Klimovich A. O. Dolinkin E. V. Parfenova K. A. Rubina |
| author_facet | E. V. Semina P. S. Klimovich A. O. Dolinkin E. V. Parfenova K. A. Rubina |
| author_sort | E. V. Semina |
| collection | DOAJ |
| description | Today technologies stimulating growth and stabilization of new blood vessel, regulating trajectory of vascular growth are promising for the treatment of ischemia. These technologies represent a therapeutic angiogenesis. Its are essential in the rapidly developing regenerative medicine. In the present work we describe the development and validation methods for determining the specific impurities (purity) gene therapeutic drug using the electrophoresis method in agarose gel followed by densitometry of electrophoretogram. This drug is designed for the treatment of lower limb ischemia. This drug is a combination preparation containing a mixture of DNA plasmid encoding the gene of hepatocyte growth factor and gene of Angiopoietin-1. |
| format | Article |
| id | doaj-art-985745fe1eb747ecb0d5ff917f646284 |
| institution | Kabale University |
| issn | 2305-2066 2658-5049 |
| language | Russian |
| publishDate | 2019-01-01 |
| publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
| record_format | Article |
| series | Разработка и регистрация лекарственных средств |
| spelling | doaj-art-985745fe1eb747ecb0d5ff917f6462842025-08-20T03:59:20ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-0102869288FEATURES OF QUALITY ASSESSMENT AND STANDARDIZATION PROSPECTS OF FATTY OILS AND OIL EXTRACTS FOR PHARMACEUTICAL PURPOSES (REVIEW)E. V. Semina0P. S. Klimovich1A. O. Dolinkin2E. V. Parfenova3K. A. Rubina4Department of Biochemistry and Molecular Medicine, Faculty of Medicine, M.V. Lomonosov Moscow State UniversityDepartment of Biochemistry and Molecular Medicine, Faculty of Medicine, M.V. Lomonosov Moscow State UniversityDepartment of Biochemistry and Molecular Medicine, Faculty of Medicine, M.V. Lomonosov Moscow State UniversityDepartment of Biochemistry and Molecular Medicine, Faculty of Medicine, M.V. Lomonosov Moscow State UniversityDepartment of Biochemistry and Molecular Medicine, Faculty of Medicine, M.V. Lomonosov Moscow State UniversityToday technologies stimulating growth and stabilization of new blood vessel, regulating trajectory of vascular growth are promising for the treatment of ischemia. These technologies represent a therapeutic angiogenesis. Its are essential in the rapidly developing regenerative medicine. In the present work we describe the development and validation methods for determining the specific impurities (purity) gene therapeutic drug using the electrophoresis method in agarose gel followed by densitometry of electrophoretogram. This drug is designed for the treatment of lower limb ischemia. This drug is a combination preparation containing a mixture of DNA plasmid encoding the gene of hepatocyte growth factor and gene of Angiopoietin-1.https://www.pharmjournal.ru/jour/article/view/88regenerative medicineregenerationgene therapy drugvalidation of methodrestrictionelectrophoresis |
| spellingShingle | E. V. Semina P. S. Klimovich A. O. Dolinkin E. V. Parfenova K. A. Rubina FEATURES OF QUALITY ASSESSMENT AND STANDARDIZATION PROSPECTS OF FATTY OILS AND OIL EXTRACTS FOR PHARMACEUTICAL PURPOSES (REVIEW) Разработка и регистрация лекарственных средств regenerative medicine regeneration gene therapy drug validation of method restriction electrophoresis |
| title | FEATURES OF QUALITY ASSESSMENT AND STANDARDIZATION PROSPECTS OF FATTY OILS AND OIL EXTRACTS FOR PHARMACEUTICAL PURPOSES (REVIEW) |
| title_full | FEATURES OF QUALITY ASSESSMENT AND STANDARDIZATION PROSPECTS OF FATTY OILS AND OIL EXTRACTS FOR PHARMACEUTICAL PURPOSES (REVIEW) |
| title_fullStr | FEATURES OF QUALITY ASSESSMENT AND STANDARDIZATION PROSPECTS OF FATTY OILS AND OIL EXTRACTS FOR PHARMACEUTICAL PURPOSES (REVIEW) |
| title_full_unstemmed | FEATURES OF QUALITY ASSESSMENT AND STANDARDIZATION PROSPECTS OF FATTY OILS AND OIL EXTRACTS FOR PHARMACEUTICAL PURPOSES (REVIEW) |
| title_short | FEATURES OF QUALITY ASSESSMENT AND STANDARDIZATION PROSPECTS OF FATTY OILS AND OIL EXTRACTS FOR PHARMACEUTICAL PURPOSES (REVIEW) |
| title_sort | features of quality assessment and standardization prospects of fatty oils and oil extracts for pharmaceutical purposes review |
| topic | regenerative medicine regeneration gene therapy drug validation of method restriction electrophoresis |
| url | https://www.pharmjournal.ru/jour/article/view/88 |
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