Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure
The purpose of this article is to describe the problem of predicting the lung function recovery in patients with extracorporeal membrane oxygenation for acute respiratory distress syndrome. Data from CESAR and EOLIA clinical trials on the efficacy of extracorporeal membrane oxygenation in patients w...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2020-09-01
|
| Series: | Трансплантология (Москва) |
| Subjects: | |
| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/517 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849409051357609984 |
|---|---|
| author | P. A. Brygin S. V. Zhuravel D. A. Troitskiy I. I. Utkina |
| author_facet | P. A. Brygin S. V. Zhuravel D. A. Troitskiy I. I. Utkina |
| author_sort | P. A. Brygin |
| collection | DOAJ |
| description | The purpose of this article is to describe the problem of predicting the lung function recovery in patients with extracorporeal membrane oxygenation for acute respiratory distress syndrome. Data from CESAR and EOLIA clinical trials on the efficacy of extracorporeal membrane oxygenation in patients with acute respiratory distress syndrome have been reviewed and some controversial results discussed. The prognostic PRESERVE and RESP scores developed as prognostic tools on the basis of the results of these studies, are presented, the limitations of their applicability in various forms of acute respiratory distress syndrome are discussed. We propose to subdivide the predictors of the extracorporeal membrane oxygenation outcome in patients with acute respiratory distress syndrome into 4 following groups: 1. Lung injury severity criteria, including parameters of their lung mechanical and functional properties. 2. Time from acute respiratory failure onset to extracorporeal membrane oxygenation initiation, which reflects the rate of pathological processes in lungs and timing of decision to initiate extracorporeal membrane oxygenation. 3. The etiology of pulmonary disorders, directly affecting the reversibility of pathological processes in the lungs. 4. The severity of the patient's general condition, including the severity of manifestations of multiple organ failure, the degree of decompensation of concomitant chronic diseases, including oncological and associated with immunosuppression. Several diseases are associated with a higher risk of specific complications, particularly hemorrhagic, during extracorporeal membrane oxygenation. |
| format | Article |
| id | doaj-art-984b00d996dc4e1c92a0d021b30a3b13 |
| institution | Kabale University |
| issn | 2074-0506 2542-0909 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj-art-984b00d996dc4e1c92a0d021b30a3b132025-08-20T03:35:37ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092020-09-0112322023010.23873/2074-0506-2020-12-3-220-230453Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failureP. A. Brygin0S. V. Zhuravel1D. A. Troitskiy2I. I. Utkina3N.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineThe purpose of this article is to describe the problem of predicting the lung function recovery in patients with extracorporeal membrane oxygenation for acute respiratory distress syndrome. Data from CESAR and EOLIA clinical trials on the efficacy of extracorporeal membrane oxygenation in patients with acute respiratory distress syndrome have been reviewed and some controversial results discussed. The prognostic PRESERVE and RESP scores developed as prognostic tools on the basis of the results of these studies, are presented, the limitations of their applicability in various forms of acute respiratory distress syndrome are discussed. We propose to subdivide the predictors of the extracorporeal membrane oxygenation outcome in patients with acute respiratory distress syndrome into 4 following groups: 1. Lung injury severity criteria, including parameters of their lung mechanical and functional properties. 2. Time from acute respiratory failure onset to extracorporeal membrane oxygenation initiation, which reflects the rate of pathological processes in lungs and timing of decision to initiate extracorporeal membrane oxygenation. 3. The etiology of pulmonary disorders, directly affecting the reversibility of pathological processes in the lungs. 4. The severity of the patient's general condition, including the severity of manifestations of multiple organ failure, the degree of decompensation of concomitant chronic diseases, including oncological and associated with immunosuppression. Several diseases are associated with a higher risk of specific complications, particularly hemorrhagic, during extracorporeal membrane oxygenation.https://www.jtransplantologiya.ru/jour/article/view/517extracorporeal membrane oxygenationacute respiratory distress syndromeacute respiratory failure |
| spellingShingle | P. A. Brygin S. V. Zhuravel D. A. Troitskiy I. I. Utkina Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure Трансплантология (Москва) extracorporeal membrane oxygenation acute respiratory distress syndrome acute respiratory failure |
| title | Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure |
| title_full | Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure |
| title_fullStr | Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure |
| title_full_unstemmed | Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure |
| title_short | Predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure |
| title_sort | predictors of extracorporeal membrane oxygenation efficacy in patients with acute respiratory failure |
| topic | extracorporeal membrane oxygenation acute respiratory distress syndrome acute respiratory failure |
| url | https://www.jtransplantologiya.ru/jour/article/view/517 |
| work_keys_str_mv | AT pabrygin predictorsofextracorporealmembraneoxygenationefficacyinpatientswithacuterespiratoryfailure AT svzhuravel predictorsofextracorporealmembraneoxygenationefficacyinpatientswithacuterespiratoryfailure AT datroitskiy predictorsofextracorporealmembraneoxygenationefficacyinpatientswithacuterespiratoryfailure AT iiutkina predictorsofextracorporealmembraneoxygenationefficacyinpatientswithacuterespiratoryfailure |