Comparative Analysis of Biomechanical Stability and Pain Reduction in Novel TLIF Devices
Objective This study aims to evaluate the biomechanical and clinical performance of a new anti-backout TLIF device compared to a traditional device.Methods This study involved a rat model, with biomechanical tests including static axial compression, static and dynamic settlement, and blade-cutting t...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | Journal of Investigative Surgery |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/08941939.2025.2520264 |
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| Summary: | Objective This study aims to evaluate the biomechanical and clinical performance of a new anti-backout TLIF device compared to a traditional device.Methods This study involved a rat model, with biomechanical tests including static axial compression, static and dynamic settlement, and blade-cutting torque tests. Pain behavior in rats (n = 6) and material compatibility through cell toxicity and hemolysis tests were also assessed.Results The modified anti-backout interbody fusion cage demonstrated a yield load of 7747.36 ± 274.96 N in static axial compression testing, significantly higher than the traditional TLIF cage’s 6933.36 ± 65.00 N (p < 0.05), indicating superior load resistance. In static settlement testing, the modified cage’s yield load was 1020.87 ± 13.22 N, also notably higher than the traditional cage’s 939.06 ± 8.03 N (p < 0.05). In static pullout testing, the maximum pullout force of the modified cage with the blade extended reached 534.02 ± 21.24 N, exceeding the 476.97 ± 24.45 N without the blade (p < 0.05), showing advantages in maximum pullout force and stiffness. Biocompatibility tests revealed lower cytotoxicity and a hemolysis rate of less than 5% for the modified cage material, significantly better than the traditional material’s 8% (p < 0.05).Conclusion The new anti-backout TLIF device provides enhanced stability, reduced pain, and improved material compatibility, supporting its potential for clinical application. |
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| ISSN: | 0894-1939 1521-0553 |