Preparation of a New Active Component 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub> for Potentiometric Membranes for the Determination of Terbinafine Hydrochloride
This paper presents a methodology for the preparation of a new active component for ion-selective membranes, based on a di-substituted sulfonium derivative of the <i>closo</i>-decaborate anion at the apical vertices with the octadecylalkyl substituents 1,10-B<sub>10</sub>H<...
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2025-01-01
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| Series: | Inorganics |
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| Online Access: | https://www.mdpi.com/2304-6740/13/2/35 |
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| author | Eugeniy S. Turyshev Alexey V. Golubev Alexander Yu. Bykov Konstantin Yu. Zhizhin Nikolay T. Kuznetsov |
| author_facet | Eugeniy S. Turyshev Alexey V. Golubev Alexander Yu. Bykov Konstantin Yu. Zhizhin Nikolay T. Kuznetsov |
| author_sort | Eugeniy S. Turyshev |
| collection | DOAJ |
| description | This paper presents a methodology for the preparation of a new active component for ion-selective membranes, based on a di-substituted sulfonium derivative of the <i>closo</i>-decaborate anion at the apical vertices with the octadecylalkyl substituents 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub>. This approach is characterized by physicochemical methods of analysis (11B, 1H, 13C NMR spectroscopy, IR spectroscopy and elemental analysis). The compound obtained is used as an active component of a PVC membrane selective to terbinafine hydrochloride. The sensor developed is highly selective to the drug to be detected, has a linearity range of 4.0 × 10<sup>−8</sup>–1.0 × 10<sup>−2</sup> and a detection limit of 1.0 × 10<sup>−8</sup>, and can detect terbinafine hydrochloride in the pH range of 3 to 6. |
| format | Article |
| id | doaj-art-9841285759004876a8dfdf9ef419cde8 |
| institution | DOAJ |
| issn | 2304-6740 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Inorganics |
| spelling | doaj-art-9841285759004876a8dfdf9ef419cde82025-08-20T03:12:15ZengMDPI AGInorganics2304-67402025-01-011323510.3390/inorganics13020035Preparation of a New Active Component 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub> for Potentiometric Membranes for the Determination of Terbinafine HydrochlorideEugeniy S. Turyshev0Alexey V. Golubev1Alexander Yu. Bykov2Konstantin Yu. Zhizhin3Nikolay T. Kuznetsov4Institute for African Studies of the Russian Academy of Sciences (IAS), st. Spiridonovka 30/1, Moscow 123001, RussiaN.S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninskii pr.31, Moscow 119991, RussiaN.S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninskii pr.31, Moscow 119991, RussiaN.S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninskii pr.31, Moscow 119991, RussiaN.S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninskii pr.31, Moscow 119991, RussiaThis paper presents a methodology for the preparation of a new active component for ion-selective membranes, based on a di-substituted sulfonium derivative of the <i>closo</i>-decaborate anion at the apical vertices with the octadecylalkyl substituents 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub>. This approach is characterized by physicochemical methods of analysis (11B, 1H, 13C NMR spectroscopy, IR spectroscopy and elemental analysis). The compound obtained is used as an active component of a PVC membrane selective to terbinafine hydrochloride. The sensor developed is highly selective to the drug to be detected, has a linearity range of 4.0 × 10<sup>−8</sup>–1.0 × 10<sup>−2</sup> and a detection limit of 1.0 × 10<sup>−8</sup>, and can detect terbinafine hydrochloride in the pH range of 3 to 6.https://www.mdpi.com/2304-6740/13/2/35polymersion-selective membraneboron clusterssulfanyl derivativeterbinafine |
| spellingShingle | Eugeniy S. Turyshev Alexey V. Golubev Alexander Yu. Bykov Konstantin Yu. Zhizhin Nikolay T. Kuznetsov Preparation of a New Active Component 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub> for Potentiometric Membranes for the Determination of Terbinafine Hydrochloride Inorganics polymers ion-selective membrane boron clusters sulfanyl derivative terbinafine |
| title | Preparation of a New Active Component 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub> for Potentiometric Membranes for the Determination of Terbinafine Hydrochloride |
| title_full | Preparation of a New Active Component 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub> for Potentiometric Membranes for the Determination of Terbinafine Hydrochloride |
| title_fullStr | Preparation of a New Active Component 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub> for Potentiometric Membranes for the Determination of Terbinafine Hydrochloride |
| title_full_unstemmed | Preparation of a New Active Component 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub> for Potentiometric Membranes for the Determination of Terbinafine Hydrochloride |
| title_short | Preparation of a New Active Component 1,10-B<sub>10</sub>H<sub>8</sub>(S(C<sub>18</sub>H<sub>37</sub>)<sub>2</sub>)<sub>2</sub> for Potentiometric Membranes for the Determination of Terbinafine Hydrochloride |
| title_sort | preparation of a new active component 1 10 b sub 10 sub h sub 8 sub s c sub 18 sub h sub 37 sub sub 2 sub sub 2 sub for potentiometric membranes for the determination of terbinafine hydrochloride |
| topic | polymers ion-selective membrane boron clusters sulfanyl derivative terbinafine |
| url | https://www.mdpi.com/2304-6740/13/2/35 |
| work_keys_str_mv | AT eugeniysturyshev preparationofanewactivecomponent110bsub10subhsub8subscsub18subhsub37subsub2subsub2subforpotentiometricmembranesforthedeterminationofterbinafinehydrochloride AT alexeyvgolubev preparationofanewactivecomponent110bsub10subhsub8subscsub18subhsub37subsub2subsub2subforpotentiometricmembranesforthedeterminationofterbinafinehydrochloride AT alexanderyubykov preparationofanewactivecomponent110bsub10subhsub8subscsub18subhsub37subsub2subsub2subforpotentiometricmembranesforthedeterminationofterbinafinehydrochloride AT konstantinyuzhizhin preparationofanewactivecomponent110bsub10subhsub8subscsub18subhsub37subsub2subsub2subforpotentiometricmembranesforthedeterminationofterbinafinehydrochloride AT nikolaytkuznetsov preparationofanewactivecomponent110bsub10subhsub8subscsub18subhsub37subsub2subsub2subforpotentiometricmembranesforthedeterminationofterbinafinehydrochloride |