Genetic insights into BRCA1/2 associated breast cancer in Türkiye: focus on early-onset and aggressive subtypes

Genetic insights into BRCA1/2 associated breast cancer in Türkiye: focus on early-onset and aggressive subtypes

Abstract Aim The prevalence of BRCA1/2 pathogenic variants among Turkish breast cancer (BC) patients is not well-characterized. We specifically examine the age at onset and cancer sub-types concerning BRCA1/2 mutation status, focusing on patients with no family history of breast or ovarian cancer. M...

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Main Authors: Betul Celik Demirbas, Seda Kilic Erciyas, Ozge Sukruoglu Erdogan, Ozge Pasin, Zubeyde Yalniz Kayim, Merve Çiğdem Özgel, Seref Bugra Tuncer
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
BRCA1/2 mutations
Breast cancer
HER2 positive
Triple-negative breast cancer (TNBC)
Turkish population
Online Access:https://doi.org/10.1007/s12672-025-02192-0
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