Development of a latency model for HIV-1 subtype C and the impact of long terminal repeat element genetic variation on latency reversal

Development of a latency model for HIV-1 subtype C and the impact of long terminal repeat element genetic variation on latency reversal

Sub-Saharan Africa accounts for almost 70 % of people living with HIV (PLWH) worldwide, with the greatest numbers centred in South Africa where 98 % of infections are caused by subtype C (HIV-1C). However, HIV-1 subtype B (HIV-1B), prevalent in Europe and North America, has been the focus of most cu...

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Bibliographic Details
Main Authors: Shreyal Maikoo, Robert-Jan Palstra, Krista L. Dong, Tokameh Mahmoudi, Thumbi Ndung'u, Paradise Madlala
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Virus Eradication
Subjects:
Genetic variation
HIV-1C latency
HIV-1 subtype C
Reactivation
Transmitted founder (T/F)
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664024001900
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