Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study
Conclusions: The interaction of the rs7901695 site of the TCF7L2 gene and the cg06500161 site of the ABCG1 gene with environmental factors may increase the risk of T2DM in Uyghurs. The interaction between the cg06500161 site of the ABCG1 gene and environmental factors on T2DM varied with the interve...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/jdr/9356676 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850184813639630848 |
|---|---|
| author | Yinxia Su Bo Shang Xiaoyuan Hu Zhihao Zhang Li Wang Kun Luo Hua Yao Xiangtao Liu Yaoqin Lu Sheng Jiang |
| author_facet | Yinxia Su Bo Shang Xiaoyuan Hu Zhihao Zhang Li Wang Kun Luo Hua Yao Xiangtao Liu Yaoqin Lu Sheng Jiang |
| author_sort | Yinxia Su |
| collection | DOAJ |
| description | Conclusions: The interaction of the rs7901695 site of the TCF7L2 gene and the cg06500161 site of the ABCG1 gene with environmental factors may increase the risk of T2DM in Uyghurs. The interaction between the cg06500161 site of the ABCG1 gene and environmental factors on T2DM varied with the intervention. The cg06500161 site of ABCG1 may serve as a biomarker to evaluate the effect of T2DM interventions. |
| format | Article |
| id | doaj-art-98244d2cfc1a42458e070bb15bdbd85c |
| institution | OA Journals |
| issn | 2314-6753 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-98244d2cfc1a42458e070bb15bdbd85c2025-08-20T02:16:55ZengWileyJournal of Diabetes Research2314-67532025-01-01202510.1155/jdr/9356676Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control StudyYinxia Su0Bo Shang1Xiaoyuan Hu2Zhihao Zhang3Li Wang4Kun Luo5Hua Yao6Xiangtao Liu7Yaoqin Lu8Sheng Jiang9State Key Laboratory of PathogenesisSchool of Medical Engineering and TechnologyDepartment of Hospital AdministrationSchool of Medical Engineering and TechnologyThe Clinical Medicine Research InstituteDepartment of Hospital AdministrationSchool of Health ManagementSchool of Medical Engineering and TechnologyDepartment of Hospital AdministrationDepartment of Hospital AdministrationConclusions: The interaction of the rs7901695 site of the TCF7L2 gene and the cg06500161 site of the ABCG1 gene with environmental factors may increase the risk of T2DM in Uyghurs. The interaction between the cg06500161 site of the ABCG1 gene and environmental factors on T2DM varied with the intervention. The cg06500161 site of ABCG1 may serve as a biomarker to evaluate the effect of T2DM interventions.http://dx.doi.org/10.1155/jdr/9356676 |
| spellingShingle | Yinxia Su Bo Shang Xiaoyuan Hu Zhihao Zhang Li Wang Kun Luo Hua Yao Xiangtao Liu Yaoqin Lu Sheng Jiang Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study Journal of Diabetes Research |
| title | Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study |
| title_full | Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study |
| title_fullStr | Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study |
| title_full_unstemmed | Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study |
| title_short | Association Between ABCG1/TCF7L2 and Type 2 Diabetes Mellitus: An Intervention Trial Based on a Case–Control Study |
| title_sort | association between abcg1 tcf7l2 and type 2 diabetes mellitus an intervention trial based on a case control study |
| url | http://dx.doi.org/10.1155/jdr/9356676 |
| work_keys_str_mv | AT yinxiasu associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT boshang associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT xiaoyuanhu associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT zhihaozhang associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT liwang associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT kunluo associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT huayao associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT xiangtaoliu associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT yaoqinlu associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy AT shengjiang associationbetweenabcg1tcf7l2andtype2diabetesmellitusaninterventiontrialbasedonacasecontrolstudy |