Point Prevalence Surveys of Antimicrobial Prescribing in a Non-Acute Care Hospital in Saitama Prefecture, Japan
Background. The global point prevalence survey (Global-PPS) is the standard for the surveillance of prescribed antimicrobials among inpatients and provides data for the development of hospital antimicrobial stewardship programs. Aim. To evaluate the prevalence and quality of antimicrobial prescripti...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2022/2497869 |
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| author | Noriomi Ishibashi Ines Pauwels Yuki Tomori Yoshiaki Gu Takefumi Yamaguchi Takahiro Handa Minoru Yamaoka Daisuke Ito Takehiko Sakimoto Takuma Kimura Kouichi Takizawa Ryota Sato Takahiro Sakashita Akira Ooyama Ann Versporten Herman Goossens Norihito Tarumoto Shigefumi Maesaki Norio Tanahashi |
| author_facet | Noriomi Ishibashi Ines Pauwels Yuki Tomori Yoshiaki Gu Takefumi Yamaguchi Takahiro Handa Minoru Yamaoka Daisuke Ito Takehiko Sakimoto Takuma Kimura Kouichi Takizawa Ryota Sato Takahiro Sakashita Akira Ooyama Ann Versporten Herman Goossens Norihito Tarumoto Shigefumi Maesaki Norio Tanahashi |
| author_sort | Noriomi Ishibashi |
| collection | DOAJ |
| description | Background. The global point prevalence survey (Global-PPS) is the standard for the surveillance of prescribed antimicrobials among inpatients and provides data for the development of hospital antimicrobial stewardship programs. Aim. To evaluate the prevalence and quality of antimicrobial prescriptions using the universally standardized Global-PPS protocol in a non-acute care hospital in Saitama Prefecture, Japan. Methods. Antimicrobial prescriptions for inpatients, staying at the hospital overnight, were surveyed on three separate week days in November 2018, January 2019, and May 2019. Information on the prescribed antimicrobials on the survey target day was obtained from the in-hospital pharmacy. Survey data were collected by physicians, based on the extracted information. Patient information was anonymized and entered in the Global-PPS Web application by physicians. We report the antimicrobial use prevalence, the indication for prescription, diagnosis, the most prescribed antimicrobials, and a set of quality indicators related to antimicrobial prescribing. Results. In total, 6.7% of the surveyed inpatients (120/1796) were prescribed antimicrobials on the survey day. Sulfamethoxazole/trimethoprim was the most commonly prescribed, with 20.0% of systemic antibiotic prescriptions (ATC J01). Of all antibiotics for systemic use, up to 58.4% were Watch antibiotics, as defined by the World Health Organization AWaRe classification. The most prescribed group of systemic antibiotics was non-penicillin beta-lactam antibiotics (34.4%), followed by penicillin antibiotics in combination with beta-lactamase inhibitors (25.6%), and sulfonamides with trimethoprim (20.8%). Healthcare-associated infections and medical prophylaxis were the most common indications reported in 69.3% and 26.3% of prescriptions, respectively. The most common diagnosis for systemic antibiotic prescriptions was pneumonia (49.6%). Reasons for antimicrobial prescriptions were indicated in the medical records for 67.1% of prescriptions, and the stop/review date was documented to be 50.3%. Compliance with local guidelines reached 66.7%. Conclusions. This study highlights important challenges related to antimicrobial prescription in a highly specific, non-acute care patient population. |
| format | Article |
| id | doaj-art-98228a781a2540a98aae79e1e8deeef2 |
| institution | Kabale University |
| issn | 1918-1493 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-98228a781a2540a98aae79e1e8deeef22025-08-20T03:37:22ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932022-01-01202210.1155/2022/2497869Point Prevalence Surveys of Antimicrobial Prescribing in a Non-Acute Care Hospital in Saitama Prefecture, JapanNoriomi Ishibashi0Ines Pauwels1Yuki Tomori2Yoshiaki Gu3Takefumi Yamaguchi4Takahiro Handa5Minoru Yamaoka6Daisuke Ito7Takehiko Sakimoto8Takuma Kimura9Kouichi Takizawa10Ryota Sato11Takahiro Sakashita12Akira Ooyama13Ann Versporten14Herman Goossens15Norihito Tarumoto16Shigefumi Maesaki17Norio Tanahashi18Department of Infectious Disease and Infection ControlLaboratory of Medical MicrobiologyDepartment of Internal MedicineDepartment of Infectious DiseasesDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of PharmacyDepartment of PharmacyDepartment of PharmacyLaboratory of Medical MicrobiologyLaboratory of Medical MicrobiologyDepartment of Infectious Disease and Infection ControlDepartment of Infectious Disease and Infection ControlDepartment of NeurologyBackground. The global point prevalence survey (Global-PPS) is the standard for the surveillance of prescribed antimicrobials among inpatients and provides data for the development of hospital antimicrobial stewardship programs. Aim. To evaluate the prevalence and quality of antimicrobial prescriptions using the universally standardized Global-PPS protocol in a non-acute care hospital in Saitama Prefecture, Japan. Methods. Antimicrobial prescriptions for inpatients, staying at the hospital overnight, were surveyed on three separate week days in November 2018, January 2019, and May 2019. Information on the prescribed antimicrobials on the survey target day was obtained from the in-hospital pharmacy. Survey data were collected by physicians, based on the extracted information. Patient information was anonymized and entered in the Global-PPS Web application by physicians. We report the antimicrobial use prevalence, the indication for prescription, diagnosis, the most prescribed antimicrobials, and a set of quality indicators related to antimicrobial prescribing. Results. In total, 6.7% of the surveyed inpatients (120/1796) were prescribed antimicrobials on the survey day. Sulfamethoxazole/trimethoprim was the most commonly prescribed, with 20.0% of systemic antibiotic prescriptions (ATC J01). Of all antibiotics for systemic use, up to 58.4% were Watch antibiotics, as defined by the World Health Organization AWaRe classification. The most prescribed group of systemic antibiotics was non-penicillin beta-lactam antibiotics (34.4%), followed by penicillin antibiotics in combination with beta-lactamase inhibitors (25.6%), and sulfonamides with trimethoprim (20.8%). Healthcare-associated infections and medical prophylaxis were the most common indications reported in 69.3% and 26.3% of prescriptions, respectively. The most common diagnosis for systemic antibiotic prescriptions was pneumonia (49.6%). Reasons for antimicrobial prescriptions were indicated in the medical records for 67.1% of prescriptions, and the stop/review date was documented to be 50.3%. Compliance with local guidelines reached 66.7%. Conclusions. This study highlights important challenges related to antimicrobial prescription in a highly specific, non-acute care patient population.http://dx.doi.org/10.1155/2022/2497869 |
| spellingShingle | Noriomi Ishibashi Ines Pauwels Yuki Tomori Yoshiaki Gu Takefumi Yamaguchi Takahiro Handa Minoru Yamaoka Daisuke Ito Takehiko Sakimoto Takuma Kimura Kouichi Takizawa Ryota Sato Takahiro Sakashita Akira Ooyama Ann Versporten Herman Goossens Norihito Tarumoto Shigefumi Maesaki Norio Tanahashi Point Prevalence Surveys of Antimicrobial Prescribing in a Non-Acute Care Hospital in Saitama Prefecture, Japan Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Point Prevalence Surveys of Antimicrobial Prescribing in a Non-Acute Care Hospital in Saitama Prefecture, Japan |
| title_full | Point Prevalence Surveys of Antimicrobial Prescribing in a Non-Acute Care Hospital in Saitama Prefecture, Japan |
| title_fullStr | Point Prevalence Surveys of Antimicrobial Prescribing in a Non-Acute Care Hospital in Saitama Prefecture, Japan |
| title_full_unstemmed | Point Prevalence Surveys of Antimicrobial Prescribing in a Non-Acute Care Hospital in Saitama Prefecture, Japan |
| title_short | Point Prevalence Surveys of Antimicrobial Prescribing in a Non-Acute Care Hospital in Saitama Prefecture, Japan |
| title_sort | point prevalence surveys of antimicrobial prescribing in a non acute care hospital in saitama prefecture japan |
| url | http://dx.doi.org/10.1155/2022/2497869 |
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