Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine
Considering the importance of pain, this study aims to present a standard topical formulation for pain control. In the texts of traditional Persian pharmaceutical books, many verbs, and citrus fruits are mentioned as pain relievers. In this study, the Plantago ovata Forsk. plant was selected from th...
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Shiraz University of Medical Sciences
2024-12-01
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| Series: | Trends in Pharmaceutical Sciences |
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| Online Access: | https://tips.sums.ac.ir/article_50640_cc0c4e43c04231f4eed58a4d0be95a3e.pdf |
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| author | Amirhossein Zamani Aida Alipour Mohammad M. Zarshenas Hajar Ashrafi |
| author_facet | Amirhossein Zamani Aida Alipour Mohammad M. Zarshenas Hajar Ashrafi |
| author_sort | Amirhossein Zamani |
| collection | DOAJ |
| description | Considering the importance of pain, this study aims to present a standard topical formulation for pain control. In the texts of traditional Persian pharmaceutical books, many verbs, and citrus fruits are mentioned as pain relievers. In this study, the Plantago ovata Forsk. plant was selected from the book of Makhzen al-Adviyah, and related aqueous and acidic extractions were yielded in rose oil. After microscopic characterization and determining the identification number of the plant and FTIR test, Plantago ovata Forsk seed extract was prepared with different acidic and aqueous types, and the mucilage was prepared after evaluating several cream formulations, finally, the proportion of 70% oil and 30% stearic acid contained 65% extract. It was chosen as the appropriate formulation, which was more suitable for appearance characteristics (uniform texture and proper spreading without feeling rough on the skin). The final semi-solid formulation was examined in terms of the uniformity and integrity of the cream and the examination of rubability and cream consistency tests, the examination of spreadability, pH measurement, and the examination of viscosity and rheology properties, and the results showed that this formulation in terms of pharmaceutics tests and the total saccharide content was in the acceptable range. After passing the clinical trials, the mentioned product can be effective as a product derived from herbal compounds for pain control. |
| format | Article |
| id | doaj-art-9821221523d44b5d8153ea73d482390b |
| institution | Kabale University |
| issn | 2423-5652 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Trends in Pharmaceutical Sciences |
| spelling | doaj-art-9821221523d44b5d8153ea73d482390b2025-02-09T08:20:03ZengShiraz University of Medical SciencesTrends in Pharmaceutical Sciences2423-56522024-12-0110434335410.30476/tips.2025.104471.126450640Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory MedicineAmirhossein Zamani0Aida Alipour1Mohammad M. Zarshenas2Hajar Ashrafi3Student Research Committee, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.Student Research Committee, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.Considering the importance of pain, this study aims to present a standard topical formulation for pain control. In the texts of traditional Persian pharmaceutical books, many verbs, and citrus fruits are mentioned as pain relievers. In this study, the Plantago ovata Forsk. plant was selected from the book of Makhzen al-Adviyah, and related aqueous and acidic extractions were yielded in rose oil. After microscopic characterization and determining the identification number of the plant and FTIR test, Plantago ovata Forsk seed extract was prepared with different acidic and aqueous types, and the mucilage was prepared after evaluating several cream formulations, finally, the proportion of 70% oil and 30% stearic acid contained 65% extract. It was chosen as the appropriate formulation, which was more suitable for appearance characteristics (uniform texture and proper spreading without feeling rough on the skin). The final semi-solid formulation was examined in terms of the uniformity and integrity of the cream and the examination of rubability and cream consistency tests, the examination of spreadability, pH measurement, and the examination of viscosity and rheology properties, and the results showed that this formulation in terms of pharmaceutics tests and the total saccharide content was in the acceptable range. After passing the clinical trials, the mentioned product can be effective as a product derived from herbal compounds for pain control.https://tips.sums.ac.ir/article_50640_cc0c4e43c04231f4eed58a4d0be95a3e.pdfanalgesicmedicinal plantspaintopical |
| spellingShingle | Amirhossein Zamani Aida Alipour Mohammad M. Zarshenas Hajar Ashrafi Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine Trends in Pharmaceutical Sciences analgesic medicinal plants pain topical |
| title | Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine |
| title_full | Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine |
| title_fullStr | Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine |
| title_full_unstemmed | Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine |
| title_short | Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine |
| title_sort | design and preparing a topical semi solid formulation of a combination of plantago ovata seeds and rosehip oil to provide an analgesic and anti inflammatory medicine |
| topic | analgesic medicinal plants pain topical |
| url | https://tips.sums.ac.ir/article_50640_cc0c4e43c04231f4eed58a4d0be95a3e.pdf |
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