IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
The results of correction of immune status in patients with pyo-necrotic forms of diabetic foot are presented. It is established that the clinical signs of secondary immune deficiency in patients with pyo-necrotic forms of diabetic foot are accompanied by changes in laboratory immunological paramete...
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| Format: | Article |
| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2015-06-01
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| Series: | Кубанский научный медицинский вестник |
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| Online Access: | https://ksma.elpub.ru/jour/article/view/326 |
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| author | R. V. Eselevich A. N. Lipin N. V. Ruhlyada I. A. Solovyev |
| author_facet | R. V. Eselevich A. N. Lipin N. V. Ruhlyada I. A. Solovyev |
| author_sort | R. V. Eselevich |
| collection | DOAJ |
| description | The results of correction of immune status in patients with pyo-necrotic forms of diabetic foot are presented. It is established that the clinical signs of secondary immune deficiency in patients with pyo-necrotic forms of diabetic foot are accompanied by changes in laboratory immunological parameters: the presence of relative and absolute lymphopenia; reduction in the relative and absolute T-lymphocyte numbers, and of subpopulations of CD4 lymphocytes, as well as levels of phagocytosis. The data presented indicates that inclusion of immunomodulators into the treatment program in patients with pyo-necrotic forms of diabetic foot led to a reduction in treatment time, complications, and to positive changes in the parameters characterizing the state of the immune system. |
| format | Article |
| id | doaj-art-981f8088ba114ef19e9978ecda1fd5e9 |
| institution | Kabale University |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| publishDate | 2015-06-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj-art-981f8088ba114ef19e9978ecda1fd5e92025-08-20T03:57:13ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442015-06-0134954326IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROMER. V. Eselevich0A. N. Lipin1N. V. Ruhlyada2I. A. Solovyev3Kirov Military medical academyKirov Military medical academyKirov Military medical academyKirov Military medical academyThe results of correction of immune status in patients with pyo-necrotic forms of diabetic foot are presented. It is established that the clinical signs of secondary immune deficiency in patients with pyo-necrotic forms of diabetic foot are accompanied by changes in laboratory immunological parameters: the presence of relative and absolute lymphopenia; reduction in the relative and absolute T-lymphocyte numbers, and of subpopulations of CD4 lymphocytes, as well as levels of phagocytosis. The data presented indicates that inclusion of immunomodulators into the treatment program in patients with pyo-necrotic forms of diabetic foot led to a reduction in treatment time, complications, and to positive changes in the parameters characterizing the state of the immune system.https://ksma.elpub.ru/jour/article/view/326сахарный диабетсиндром диабетической стопыдиабетическая гангренаиммунитетвторичная иммунная недостаточностьиммунокоррекциясиндром системной воспалительной реакциилечениеdiabetes mellitusdiabetic foot syndromediabetic gangreneimmunitysecondary immunodeficiencyimmunocorrectionsystemic inflammatory response syndrometreatment |
| spellingShingle | R. V. Eselevich A. N. Lipin N. V. Ruhlyada I. A. Solovyev IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME Кубанский научный медицинский вестник сахарный диабет синдром диабетической стопы диабетическая гангрена иммунитет вторичная иммунная недостаточность иммунокоррекция синдром системной воспалительной реакции лечение diabetes mellitus diabetic foot syndrome diabetic gangrene immunity secondary immunodeficiency immunocorrection systemic inflammatory response syndrome treatment |
| title | IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME |
| title_full | IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME |
| title_fullStr | IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME |
| title_full_unstemmed | IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME |
| title_short | IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME |
| title_sort | immunotropic therapy in the complex treatment of patients with diabetic foot syndrome |
| topic | сахарный диабет синдром диабетической стопы диабетическая гангрена иммунитет вторичная иммунная недостаточность иммунокоррекция синдром системной воспалительной реакции лечение diabetes mellitus diabetic foot syndrome diabetic gangrene immunity secondary immunodeficiency immunocorrection systemic inflammatory response syndrome treatment |
| url | https://ksma.elpub.ru/jour/article/view/326 |
| work_keys_str_mv | AT rveselevich immunotropictherapyinthecomplextreatmentofpatientswithdiabeticfootsyndrome AT anlipin immunotropictherapyinthecomplextreatmentofpatientswithdiabeticfootsyndrome AT nvruhlyada immunotropictherapyinthecomplextreatmentofpatientswithdiabeticfootsyndrome AT iasolovyev immunotropictherapyinthecomplextreatmentofpatientswithdiabeticfootsyndrome |