Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in Uganda
Abstract Background Antimicrobial resistance (AMR) remains a public health threat especially in low-and-middle-income countries (LMICs). Urban slum dwellers are at higher risk of developing AMR than the general population. The aim of this study was to assess the knowledge, attitude and practices (KA...
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BMC
2025-02-01
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| Series: | Antimicrobial Resistance and Infection Control |
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| Online Access: | https://doi.org/10.1186/s13756-025-01517-6 |
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| author | Regina Ndagire Ekwaro A. Obuku Ivan Segawa Fiona Atim Catherine Nassozi Lwanira Rachel Nante Wangi Moses Ocan |
| author_facet | Regina Ndagire Ekwaro A. Obuku Ivan Segawa Fiona Atim Catherine Nassozi Lwanira Rachel Nante Wangi Moses Ocan |
| author_sort | Regina Ndagire |
| collection | DOAJ |
| description | Abstract Background Antimicrobial resistance (AMR) remains a public health threat especially in low-and-middle-income countries (LMICs). Urban slum dwellers are at higher risk of developing AMR than the general population. The aim of this study was to assess the knowledge, attitude and practices (KAP) regarding antibiotic use and AMR and the associated socio-demographic determinants among urban slum dwellers in Uganda. Methods A cross sectional study was conducted among 371 adults of Bwaise slum in Uganda selected through multi-stage cluster sampling techniques. An interviewer administered questionnaire was used to collect data on participants’ socio-demographics, KAP regarding antibiotic use and AMR. The responses to the KAP were aggregated into scores for each participant which were later dichotomized by the mean to form the predictors variables. Analysis was done in STATA 17.0. A modified Poisson regression model was used to determine predictors of each of KAP, while considering a 5% significance level. Results The study enrolled 371 participants of which 238(64.2%) were females. The median (IQR) age of the participants was 31 [24, 40] years. Over half of the respondents, 205(55.3%) were married and 157(42.3%) had primary level education. Of all participants, 177 (47.7%), 184 (49.6%) and 205 (55.3%) had good knowledge, a positive attitude and good practices regarding antibiotic use and AMR respectively. Being single (aPR = 0.75, p-value = 0.040) was negatively associated with good knowledge of antibiotic use and resistance, while having acquired tertiary education level (aPR = 1.88, p-value < 0.001) and self-employed (aPR = 1.36, p = 0.017) were associated with good knowledge of antibiotic use and resistance. Male gender (aPR = 1.25, p-value = 0.036) and monthly income < 300,000 UGX (aPR = 1.42, p-value = 0.003) were associated with a positive attitude towards antibiotic use and resistance. Likewise tertiary level of education (aPR = 0.64, p-value = 0.033) was negatively associated with good practices of antibiotic use and resistance. Conclusion and recommendations Residents of urban slums have limited knowledge of antibiotic use and AMR with minimal understanding of AMR concepts. Education level, gender, occupational status are key players in people’s understanding and practices of antibiotic use and AMR. There’s need for context specific health education programs. Health promotion messaging should emphasize AMR concepts and dangers of drug misuse. Antimicrobial stewardship initiatives should trickle down to the local citizen. |
| format | Article |
| id | doaj-art-9813b99c00fd4a6ebcb9c4c02dfd9f0e |
| institution | DOAJ |
| issn | 2047-2994 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
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| series | Antimicrobial Resistance and Infection Control |
| spelling | doaj-art-9813b99c00fd4a6ebcb9c4c02dfd9f0e2025-08-20T03:10:50ZengBMCAntimicrobial Resistance and Infection Control2047-29942025-02-0114111110.1186/s13756-025-01517-6Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in UgandaRegina Ndagire0Ekwaro A. Obuku1Ivan Segawa2Fiona Atim3Catherine Nassozi Lwanira4Rachel Nante Wangi5Moses Ocan6Africa Center for Systematic Reviews and Knowledge Translation, Makerere University College of Health SciencesAfrica Center for Systematic Reviews and Knowledge Translation, Makerere University College of Health SciencesClinical Epidemiology Unit, Makerere University College of Health SciencesSchool of Graduate Studies, Research and Innovations, Clarke International UniversitySchool of Graduate Studies, Research and Innovations, Clarke International UniversityAfrica Center for Systematic Reviews and Knowledge Translation, Makerere University College of Health SciencesAfrica Center for Systematic Reviews and Knowledge Translation, Makerere University College of Health SciencesAbstract Background Antimicrobial resistance (AMR) remains a public health threat especially in low-and-middle-income countries (LMICs). Urban slum dwellers are at higher risk of developing AMR than the general population. The aim of this study was to assess the knowledge, attitude and practices (KAP) regarding antibiotic use and AMR and the associated socio-demographic determinants among urban slum dwellers in Uganda. Methods A cross sectional study was conducted among 371 adults of Bwaise slum in Uganda selected through multi-stage cluster sampling techniques. An interviewer administered questionnaire was used to collect data on participants’ socio-demographics, KAP regarding antibiotic use and AMR. The responses to the KAP were aggregated into scores for each participant which were later dichotomized by the mean to form the predictors variables. Analysis was done in STATA 17.0. A modified Poisson regression model was used to determine predictors of each of KAP, while considering a 5% significance level. Results The study enrolled 371 participants of which 238(64.2%) were females. The median (IQR) age of the participants was 31 [24, 40] years. Over half of the respondents, 205(55.3%) were married and 157(42.3%) had primary level education. Of all participants, 177 (47.7%), 184 (49.6%) and 205 (55.3%) had good knowledge, a positive attitude and good practices regarding antibiotic use and AMR respectively. Being single (aPR = 0.75, p-value = 0.040) was negatively associated with good knowledge of antibiotic use and resistance, while having acquired tertiary education level (aPR = 1.88, p-value < 0.001) and self-employed (aPR = 1.36, p = 0.017) were associated with good knowledge of antibiotic use and resistance. Male gender (aPR = 1.25, p-value = 0.036) and monthly income < 300,000 UGX (aPR = 1.42, p-value = 0.003) were associated with a positive attitude towards antibiotic use and resistance. Likewise tertiary level of education (aPR = 0.64, p-value = 0.033) was negatively associated with good practices of antibiotic use and resistance. Conclusion and recommendations Residents of urban slums have limited knowledge of antibiotic use and AMR with minimal understanding of AMR concepts. Education level, gender, occupational status are key players in people’s understanding and practices of antibiotic use and AMR. There’s need for context specific health education programs. Health promotion messaging should emphasize AMR concepts and dangers of drug misuse. Antimicrobial stewardship initiatives should trickle down to the local citizen.https://doi.org/10.1186/s13756-025-01517-6KnowledgeAttitude and practices (KAP)Antibiotic useAntimicrobial resistanceUganda |
| spellingShingle | Regina Ndagire Ekwaro A. Obuku Ivan Segawa Fiona Atim Catherine Nassozi Lwanira Rachel Nante Wangi Moses Ocan Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in Uganda Antimicrobial Resistance and Infection Control Knowledge Attitude and practices (KAP) Antibiotic use Antimicrobial resistance Uganda |
| title | Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in Uganda |
| title_full | Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in Uganda |
| title_fullStr | Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in Uganda |
| title_full_unstemmed | Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in Uganda |
| title_short | Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in Uganda |
| title_sort | knowledge attitude and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in uganda |
| topic | Knowledge Attitude and practices (KAP) Antibiotic use Antimicrobial resistance Uganda |
| url | https://doi.org/10.1186/s13756-025-01517-6 |
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