TGF-β inhibitors: the future for prevention and treatment of liver fibrosis?

Liver fibrosis is a core pathological process in the progression of chronic liver diseases to cirrhosis and hepatocellular carcinoma, characterized by abnormal deposition of extracellular matrix. Transforming growth factor-β (TGF-β), through classical small mothers against decapentaplegic (Smad)-dep...

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Bibliographic Details
Main Authors: Weili Wang, Yilin Gao, Yizhen Chen, Meng Cheng, Yonghao Sang, Liuting Wei, Rong Dai, Yiping Wang, Lei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1583616/full
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