Features of the novel coronavirus infection in cancer patients
A novel coronavirus (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) is largely associated with various coagulopathies, which can lead to either bleeding and thrombocytopenia or hypercoagulation and thrombosis. Thrombohemorrhagic complications also could accompany the development of cancer p...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2022-01-01
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| Series: | Акушерство, гинекология и репродукция |
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| Online Access: | https://www.gynecology.su/jour/article/view/1186 |
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| author | A. D. Makatsariya I. Elalamy B. Brenner A. V. Vorobev L. A. Ashrafyan E. V. Maslenkova V. O. Bitsadze J. Kh. Khizroeva A. S. Shkoda A. G. Solopova V. N. Galkin J.-C. Gris |
| author_facet | A. D. Makatsariya I. Elalamy B. Brenner A. V. Vorobev L. A. Ashrafyan E. V. Maslenkova V. O. Bitsadze J. Kh. Khizroeva A. S. Shkoda A. G. Solopova V. N. Galkin J.-C. Gris |
| author_sort | A. D. Makatsariya |
| collection | DOAJ |
| description | A novel coronavirus (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) is largely associated with various coagulopathies, which can lead to either bleeding and thrombocytopenia or hypercoagulation and thrombosis. Thrombohemorrhagic complications also could accompany the development of cancer process. In addition, circulating inflammatory biomarkers such as fibrin, D-dimer, P-selectin and von Willebrand factor (vWF) typical to both coronavirus infection and malignancy process are of special interest. In this review, we discuss potential interplay between COVID-19 and cancer related to endothelial dysfunction, platelets, and systemic inflammatory response syndrome. Most importantly, patients should be treated in early stage of the disease process when elevated levels of fibrinogen, D-dimer, vWF, and P-selectin are observed. The level of these markers will rise rapidly upon disease progression, followed by a cytokine storm, would evidence about a poor prognosis. |
| format | Article |
| id | doaj-art-97faedcbb1a14a7487cf5d67bb9fa5fd |
| institution | DOAJ |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| publishDate | 2022-01-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj-art-97faedcbb1a14a7487cf5d67bb9fa5fd2025-08-20T03:19:14ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942022-01-0115672673710.17749/2313-7347/ob.gyn.rep.2021.249695Features of the novel coronavirus infection in cancer patientsA. D. Makatsariya0I. Elalamy1B. Brenner2A. V. Vorobev3L. A. Ashrafyan4E. V. Maslenkova5V. O. Bitsadze6J. Kh. Khizroeva7A. S. Shkoda8A. G. Solopova9V. N. Galkin10J.-C. Gris11Sechenov UniversitySechenov University; Medicine Sorbonne University; Hospital TenonRambam Academic HospitalSechenov UniversityKulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Health Ministry of Russian FederationPirogov Russian National Research Medical University, Health Ministry of Russian FederationSechenov UniversitySechenov UniversityVorokhobov City Clinical Hospital № 67, Moscow Healthcare DepartmentSechenov UniversityCity Clinical Oncological Hospital № 1, Moscow Healthcare DepartmentSechenov University; University of MontpellierA novel coronavirus (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) is largely associated with various coagulopathies, which can lead to either bleeding and thrombocytopenia or hypercoagulation and thrombosis. Thrombohemorrhagic complications also could accompany the development of cancer process. In addition, circulating inflammatory biomarkers such as fibrin, D-dimer, P-selectin and von Willebrand factor (vWF) typical to both coronavirus infection and malignancy process are of special interest. In this review, we discuss potential interplay between COVID-19 and cancer related to endothelial dysfunction, platelets, and systemic inflammatory response syndrome. Most importantly, patients should be treated in early stage of the disease process when elevated levels of fibrinogen, D-dimer, vWF, and P-selectin are observed. The level of these markers will rise rapidly upon disease progression, followed by a cytokine storm, would evidence about a poor prognosis.https://www.gynecology.su/jour/article/view/1186novel coronavirus infectioncovid-19cancerhemostasis disorderssystemic inflammatory response syndrome |
| spellingShingle | A. D. Makatsariya I. Elalamy B. Brenner A. V. Vorobev L. A. Ashrafyan E. V. Maslenkova V. O. Bitsadze J. Kh. Khizroeva A. S. Shkoda A. G. Solopova V. N. Galkin J.-C. Gris Features of the novel coronavirus infection in cancer patients Акушерство, гинекология и репродукция novel coronavirus infection covid-19 cancer hemostasis disorders systemic inflammatory response syndrome |
| title | Features of the novel coronavirus infection in cancer patients |
| title_full | Features of the novel coronavirus infection in cancer patients |
| title_fullStr | Features of the novel coronavirus infection in cancer patients |
| title_full_unstemmed | Features of the novel coronavirus infection in cancer patients |
| title_short | Features of the novel coronavirus infection in cancer patients |
| title_sort | features of the novel coronavirus infection in cancer patients |
| topic | novel coronavirus infection covid-19 cancer hemostasis disorders systemic inflammatory response syndrome |
| url | https://www.gynecology.su/jour/article/view/1186 |
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