Emerging nanotechnologies and their role in early ovarian cancer detection, diagnosis and interventions
Abstract Ovarian cancer presents a significant public health challenge, often being diagnosed at advanced stages due to the limitations of current detection methods. This systematic review addresses the urgent need for innovative approaches to enhance early detection and diagnosis of ovarian cancer....
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | Journal of Ovarian Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13048-025-01678-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849311969361788928 |
|---|---|
| author | Mega Obukohwo Oyowvi Kehinde Henrietta Babawale Adedeji David Atere Benneth Ben-Azu |
| author_facet | Mega Obukohwo Oyowvi Kehinde Henrietta Babawale Adedeji David Atere Benneth Ben-Azu |
| author_sort | Mega Obukohwo Oyowvi |
| collection | DOAJ |
| description | Abstract Ovarian cancer presents a significant public health challenge, often being diagnosed at advanced stages due to the limitations of current detection methods. This systematic review addresses the urgent need for innovative approaches to enhance early detection and diagnosis of ovarian cancer. We systematically evaluate recent advancements in nanotechnology, focusing specifically on their novel applications and potential in comparison to traditional diagnostic modalities. Our analysis encompasses a wide range of studies investigating nanoparticles, biosensors, advanced imaging techniques, and biomarker detection platforms, with an emphasis on evaluating key performance indicators such as detection rates, turnaround times, and the accuracy of distinguishing cancerous from non-cancerous tissues. Our findings indicate that nanotechnology-based approaches have the potential to significantly improve early detection capabilities for ovarian cancer. Notably, studies on nanoparticle-based imaging techniques and biosensors consistently demonstrate high sensitivity and specificity for identifying ovarian cancer biomarkers, with detection rates exceeding 90% reported for early-stage cancers in several instances. This review underscores the promise of emerging nanotechnologies to transform the landscape of early detection and diagnosis, offering a pathway toward earlier diagnoses, enhanced therapeutic interventions, and improved patient outcomes. We advocate for future research dedicated to the translational efforts required to move these technologies from bench to bedside, ensuring their effectiveness is validated across diverse clinical populations. |
| format | Article |
| id | doaj-art-97fa5330e4fe4987801725ba3db82286 |
| institution | Kabale University |
| issn | 1757-2215 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Ovarian Research |
| spelling | doaj-art-97fa5330e4fe4987801725ba3db822862025-08-20T03:53:13ZengBMCJournal of Ovarian Research1757-22152025-05-0118111010.1186/s13048-025-01678-3Emerging nanotechnologies and their role in early ovarian cancer detection, diagnosis and interventionsMega Obukohwo Oyowvi0Kehinde Henrietta Babawale1Adedeji David Atere2Benneth Ben-Azu3Department of Physiology, Adeleke UniversityDepartment of Physiology, Adeleke UniversityDepartment of Medical Laboratory Science, College of Health Sciences, Osun State UniversityDELSU Joint Canada-Israel Neuroscience and Biopsychiatry Laboratory, Department of Pharmacology, Delta State UniversityAbstract Ovarian cancer presents a significant public health challenge, often being diagnosed at advanced stages due to the limitations of current detection methods. This systematic review addresses the urgent need for innovative approaches to enhance early detection and diagnosis of ovarian cancer. We systematically evaluate recent advancements in nanotechnology, focusing specifically on their novel applications and potential in comparison to traditional diagnostic modalities. Our analysis encompasses a wide range of studies investigating nanoparticles, biosensors, advanced imaging techniques, and biomarker detection platforms, with an emphasis on evaluating key performance indicators such as detection rates, turnaround times, and the accuracy of distinguishing cancerous from non-cancerous tissues. Our findings indicate that nanotechnology-based approaches have the potential to significantly improve early detection capabilities for ovarian cancer. Notably, studies on nanoparticle-based imaging techniques and biosensors consistently demonstrate high sensitivity and specificity for identifying ovarian cancer biomarkers, with detection rates exceeding 90% reported for early-stage cancers in several instances. This review underscores the promise of emerging nanotechnologies to transform the landscape of early detection and diagnosis, offering a pathway toward earlier diagnoses, enhanced therapeutic interventions, and improved patient outcomes. We advocate for future research dedicated to the translational efforts required to move these technologies from bench to bedside, ensuring their effectiveness is validated across diverse clinical populations.https://doi.org/10.1186/s13048-025-01678-3Ovarian cancerNanocarriersNanoparticlesBiosensorsBiomarkersImaging techniques |
| spellingShingle | Mega Obukohwo Oyowvi Kehinde Henrietta Babawale Adedeji David Atere Benneth Ben-Azu Emerging nanotechnologies and their role in early ovarian cancer detection, diagnosis and interventions Journal of Ovarian Research Ovarian cancer Nanocarriers Nanoparticles Biosensors Biomarkers Imaging techniques |
| title | Emerging nanotechnologies and their role in early ovarian cancer detection, diagnosis and interventions |
| title_full | Emerging nanotechnologies and their role in early ovarian cancer detection, diagnosis and interventions |
| title_fullStr | Emerging nanotechnologies and their role in early ovarian cancer detection, diagnosis and interventions |
| title_full_unstemmed | Emerging nanotechnologies and their role in early ovarian cancer detection, diagnosis and interventions |
| title_short | Emerging nanotechnologies and their role in early ovarian cancer detection, diagnosis and interventions |
| title_sort | emerging nanotechnologies and their role in early ovarian cancer detection diagnosis and interventions |
| topic | Ovarian cancer Nanocarriers Nanoparticles Biosensors Biomarkers Imaging techniques |
| url | https://doi.org/10.1186/s13048-025-01678-3 |
| work_keys_str_mv | AT megaobukohwooyowvi emergingnanotechnologiesandtheirroleinearlyovariancancerdetectiondiagnosisandinterventions AT kehindehenriettababawale emergingnanotechnologiesandtheirroleinearlyovariancancerdetectiondiagnosisandinterventions AT adedejidavidatere emergingnanotechnologiesandtheirroleinearlyovariancancerdetectiondiagnosisandinterventions AT bennethbenazu emergingnanotechnologiesandtheirroleinearlyovariancancerdetectiondiagnosisandinterventions |