Toxic epidermal necrolysis

Objective: To recognize the common ocular signs and symptoms of toxic epidermal necrolysis (TEN), differentiate it from similar diseases, give the appropriate management, and provide continuity of care. Methods: This is a case report of a 21-year-old female patient admitted for ocular involvement...

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Main Authors: Rosalie Mae M. Reyes, MD, Jacinto Dy Liacco, MD
Format: Article
Language:English
Published: Philippine Academy of Ophthalmology 2011-06-01
Series:Philippine Journal of Ophthalmology
Subjects:
Online Access:https://paojournal.com/index.php/pjo/article/view/281
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author Rosalie Mae M. Reyes, MD
Jacinto Dy Liacco, MD
author_facet Rosalie Mae M. Reyes, MD
Jacinto Dy Liacco, MD
author_sort Rosalie Mae M. Reyes, MD
collection DOAJ
description Objective: To recognize the common ocular signs and symptoms of toxic epidermal necrolysis (TEN), differentiate it from similar diseases, give the appropriate management, and provide continuity of care. Methods: This is a case report of a 21-year-old female patient admitted for ocular involvement of TEN secondary to an acute food reaction and an adverse drug reaction to intravenous cloxacillin. Results: The patient had hyperemic conjunctivae with infiltration, mucopurulent discharge, and pseudomembrane formation with a corneal epithelial defect. The ocular symptoms were treated with copious irrigation of the conjunctival sac, daily membrane peeling, topical antibiotics, and topical steroids. The patient was advised regular follow-up to prevent symblepharon formation. Conclusion: With the appropriate diagnosis and management of TEN, ocular symptoms may be relieved and complications prevented.
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series Philippine Journal of Ophthalmology
spelling doaj-art-97f9ff1d520c4ac3938f8d0ca72789972025-08-20T03:41:57ZengPhilippine Academy of OphthalmologyPhilippine Journal of Ophthalmology0031-76592011-06-013614245281Toxic epidermal necrolysisRosalie Mae M. Reyes, MD0Jacinto Dy Liacco, MD1Department of Ophthalmology and Visual Sciences University of the Philippines– Philippine General Hospital Manila, PhilippinesDepartment of Ophthalmology and Visual Sciences University of the Philippines– Philippine General Hospital Manila, PhilippinesObjective: To recognize the common ocular signs and symptoms of toxic epidermal necrolysis (TEN), differentiate it from similar diseases, give the appropriate management, and provide continuity of care. Methods: This is a case report of a 21-year-old female patient admitted for ocular involvement of TEN secondary to an acute food reaction and an adverse drug reaction to intravenous cloxacillin. Results: The patient had hyperemic conjunctivae with infiltration, mucopurulent discharge, and pseudomembrane formation with a corneal epithelial defect. The ocular symptoms were treated with copious irrigation of the conjunctival sac, daily membrane peeling, topical antibiotics, and topical steroids. The patient was advised regular follow-up to prevent symblepharon formation. Conclusion: With the appropriate diagnosis and management of TEN, ocular symptoms may be relieved and complications prevented.https://paojournal.com/index.php/pjo/article/view/281toxic epidermal necrolysisadverse drug reactionscalded-skin syndrome
spellingShingle Rosalie Mae M. Reyes, MD
Jacinto Dy Liacco, MD
Toxic epidermal necrolysis
Philippine Journal of Ophthalmology
toxic epidermal necrolysis
adverse drug reaction
scalded-skin syndrome
title Toxic epidermal necrolysis
title_full Toxic epidermal necrolysis
title_fullStr Toxic epidermal necrolysis
title_full_unstemmed Toxic epidermal necrolysis
title_short Toxic epidermal necrolysis
title_sort toxic epidermal necrolysis
topic toxic epidermal necrolysis
adverse drug reaction
scalded-skin syndrome
url https://paojournal.com/index.php/pjo/article/view/281
work_keys_str_mv AT rosaliemaemreyesmd toxicepidermalnecrolysis
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