Immediate and Postponed Results of Short-Course Chemotherapy Regimens Containing Bedaquiline in Tuberculosis Patients with Multiple Drug Resistance
The objective: to evaluate immediate and postponed efficacy of MDR TB patients' treatment with short-course chemotherapy regimens.Subjects and Methods. Efficacy and safety of treatment with short-course chemotherapy were evaluated in 42 MDR TB patients.Results. 36 (85,7%) patients completed tre...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2023-08-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1747 |
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| author | P. N. Golubchikov T. I. Petrenko D. Yu. Schegertsov E. P. Stepanova I. I. Pravdina I. Yu. Pershina |
| author_facet | P. N. Golubchikov T. I. Petrenko D. Yu. Schegertsov E. P. Stepanova I. I. Pravdina I. Yu. Pershina |
| author_sort | P. N. Golubchikov |
| collection | DOAJ |
| description | The objective: to evaluate immediate and postponed efficacy of MDR TB patients' treatment with short-course chemotherapy regimens.Subjects and Methods. Efficacy and safety of treatment with short-course chemotherapy were evaluated in 42 MDR TB patients.Results. 36 (85,7%) patients completed treatment successfully, 1 (2,4%) patient died of non-tuberculosis, and 5 (11,9%) patients defaulted from treatment. There were no such outcomes as treatment failure and died of TB. Over the 4-year follow-up period after successful treatment completion, tuberculosis relapse was detected in 1 (1,8%) patient. No adverse events that required chemotherapy discontinuation were reported, amendment of chemotherapy regimen was required in 7 (16,7%) patients. |
| format | Article |
| id | doaj-art-97f8e86e07d7400083abbc991e5a2e82 |
| institution | DOAJ |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2023-08-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-97f8e86e07d7400083abbc991e5a2e822025-08-20T03:02:41ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062023-08-011014727910.58838/2075-1230-2023-101-4-72-791742Immediate and Postponed Results of Short-Course Chemotherapy Regimens Containing Bedaquiline in Tuberculosis Patients with Multiple Drug ResistanceP. N. Golubchikov0T. I. Petrenko1D. Yu. Schegertsov2E. P. Stepanova3I. I. Pravdina4I. Yu. Pershina5Yaya District HospitalNovosibirsk Tuberculosis Research Institute, Russian Ministry of HealthTomsk Phthisiopulmonology Medical CenterTomsk Phthisiopulmonology Medical CenterTomsk Phthisiopulmonology Medical CenterTomsk Phthisiopulmonology Medical CenterThe objective: to evaluate immediate and postponed efficacy of MDR TB patients' treatment with short-course chemotherapy regimens.Subjects and Methods. Efficacy and safety of treatment with short-course chemotherapy were evaluated in 42 MDR TB patients.Results. 36 (85,7%) patients completed treatment successfully, 1 (2,4%) patient died of non-tuberculosis, and 5 (11,9%) patients defaulted from treatment. There were no such outcomes as treatment failure and died of TB. Over the 4-year follow-up period after successful treatment completion, tuberculosis relapse was detected in 1 (1,8%) patient. No adverse events that required chemotherapy discontinuation were reported, amendment of chemotherapy regimen was required in 7 (16,7%) patients.https://www.tibl-journal.com/jour/article/view/1747pulmonary tuberculosismultiple drug resistanceshort-course chemotherapybedaquiline |
| spellingShingle | P. N. Golubchikov T. I. Petrenko D. Yu. Schegertsov E. P. Stepanova I. I. Pravdina I. Yu. Pershina Immediate and Postponed Results of Short-Course Chemotherapy Regimens Containing Bedaquiline in Tuberculosis Patients with Multiple Drug Resistance Туберкулез и болезни лёгких pulmonary tuberculosis multiple drug resistance short-course chemotherapy bedaquiline |
| title | Immediate and Postponed Results of Short-Course Chemotherapy Regimens Containing Bedaquiline in Tuberculosis Patients with Multiple Drug Resistance |
| title_full | Immediate and Postponed Results of Short-Course Chemotherapy Regimens Containing Bedaquiline in Tuberculosis Patients with Multiple Drug Resistance |
| title_fullStr | Immediate and Postponed Results of Short-Course Chemotherapy Regimens Containing Bedaquiline in Tuberculosis Patients with Multiple Drug Resistance |
| title_full_unstemmed | Immediate and Postponed Results of Short-Course Chemotherapy Regimens Containing Bedaquiline in Tuberculosis Patients with Multiple Drug Resistance |
| title_short | Immediate and Postponed Results of Short-Course Chemotherapy Regimens Containing Bedaquiline in Tuberculosis Patients with Multiple Drug Resistance |
| title_sort | immediate and postponed results of short course chemotherapy regimens containing bedaquiline in tuberculosis patients with multiple drug resistance |
| topic | pulmonary tuberculosis multiple drug resistance short-course chemotherapy bedaquiline |
| url | https://www.tibl-journal.com/jour/article/view/1747 |
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