Research progress of T lymphocytes associated with recurrent spontaneous abortion
Recurrent spontaneous abortion (RSA) is a pregnancy complication with a complex etiology that seriously affects the physical and mental health of women of reproductive age. Although RSA is commonly thought to be caused by an imbalance in maternal-fetal immune tolerance, its specific immune mechanism...
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| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Journal of Guangxi Medical University
2024-07-01
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| Series: | Guangxi Yike Daxue xuebao |
| Subjects: | |
| Online Access: | https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.07.021 |
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| Summary: | Recurrent spontaneous abortion (RSA) is a pregnancy complication with a complex etiology that seriously affects the physical and mental health of women of reproductive age. Although RSA is commonly thought to be caused by an imbalance in maternal-fetal immune tolerance, its specific immune mechanisms are not yet fully understood. Recent studies have found that an imbalance in the immune microenvironment at the maternal-fetal interface, particularly abnormalities in the function and number of T lymphocytes and their related subsets, are closely related to the occurrence of RSA. This paper aims to review the latest research progress on T lymphocyte changes in RSA, exploring the potential connections between immune cell imbalance in the maternal-fetal interface immune microenvironment and RSA, so as to provide references for basic research and clinical treatment strategies. |
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| ISSN: | 1005-930X |