Validity of heart failure diagnoses, treatments, and readmissions in the Danish National Patient Registry
Background The Danish National Patient Registry (DNPR) is a valuable resource for population-based research, but the validity of routine registration of advanced heart failure (HF) treatments within the registry is unknown. We, therefore, investigated the validity of HF, advanced HF treatments, and...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Swansea University
2024-10-01
|
| Series: | International Journal of Population Data Science |
| Subjects: | |
| Online Access: | https://ijpds.org/article/view/2394 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850192134258294784 |
|---|---|
| author | Kasper Bonnesen Christoffer Witt Brian Løgstrup Hans Eiskjær Morten Schmidt |
| author_facet | Kasper Bonnesen Christoffer Witt Brian Løgstrup Hans Eiskjær Morten Schmidt |
| author_sort | Kasper Bonnesen |
| collection | DOAJ |
| description |
Background
The Danish National Patient Registry (DNPR) is a valuable resource for population-based research, but the validity of routine registration of advanced heart failure (HF) treatments within the registry is unknown. We, therefore, investigated the validity of HF, advanced HF treatments, and HF readmissions in the DNPR.
Methods
We randomly sampled patients registered at a Danish University Hospital during 2017-2021 from the DNPR. We identified 200 patients with first-time HF, 390 patients with one of eight advanced HF treatments, and 133 patients with HF admission after implantable cardioverter-defibrillator (ICD) or cardiac resynchronisation therapy (CRT). Compared with medical record reviews, we calculated positive predictive values (PPVs) with 95 confidence intervals (CIs).
Results
The PPV for first-time HF was 81 (95 CI: 74-86). For advanced HF treatments, the PPV was 97 (95 CI: 91-99) for ICD, 96 (95 CI: 86-100) for CRT-pacemaker, 88 (95 CI: 76-95) for CRT-defibrillator, 100 (95 CI: 83-100) for left ventricular assist device, 43 (95 CI: 18-71) for intra-aortic balloon pump, 38 (95 CI: 25-35) for impella, 100 (95 CI: 93-100) for cardiopulmonary support, and 100 (95 CI: 94-100) for heart transplantation. The PPV for HF admission after ICD was 25 (95 CI: 16-37) and 18 (95 CI: 9.2-30) after CRT.
Conclusions
The PPV of routine registrations in the DNPR was moderate for first-time HF, high for most advanced HF treatments, and low for HF admissions after ICD or CRT. Thus, the DNPR is a valuable data source for population-based research on first-time HF and many advanced HF treatments.
|
| format | Article |
| id | doaj-art-97e592cbbed345df80b0eb3f9bd786a7 |
| institution | OA Journals |
| issn | 2399-4908 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Swansea University |
| record_format | Article |
| series | International Journal of Population Data Science |
| spelling | doaj-art-97e592cbbed345df80b0eb3f9bd786a72025-08-20T02:14:41ZengSwansea UniversityInternational Journal of Population Data Science2399-49082024-10-019110.23889/ijpds.v9i1.2394Validity of heart failure diagnoses, treatments, and readmissions in the Danish National Patient RegistryKasper Bonnesen0Christoffer Witt1Brian Løgstrup2Hans Eiskjær3Morten Schmidt4Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, DenmarkDepartment of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Cardiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Cardiology, Gødstrup Regional Hospital, Herning, Denmark Background The Danish National Patient Registry (DNPR) is a valuable resource for population-based research, but the validity of routine registration of advanced heart failure (HF) treatments within the registry is unknown. We, therefore, investigated the validity of HF, advanced HF treatments, and HF readmissions in the DNPR. Methods We randomly sampled patients registered at a Danish University Hospital during 2017-2021 from the DNPR. We identified 200 patients with first-time HF, 390 patients with one of eight advanced HF treatments, and 133 patients with HF admission after implantable cardioverter-defibrillator (ICD) or cardiac resynchronisation therapy (CRT). Compared with medical record reviews, we calculated positive predictive values (PPVs) with 95 confidence intervals (CIs). Results The PPV for first-time HF was 81 (95 CI: 74-86). For advanced HF treatments, the PPV was 97 (95 CI: 91-99) for ICD, 96 (95 CI: 86-100) for CRT-pacemaker, 88 (95 CI: 76-95) for CRT-defibrillator, 100 (95 CI: 83-100) for left ventricular assist device, 43 (95 CI: 18-71) for intra-aortic balloon pump, 38 (95 CI: 25-35) for impella, 100 (95 CI: 93-100) for cardiopulmonary support, and 100 (95 CI: 94-100) for heart transplantation. The PPV for HF admission after ICD was 25 (95 CI: 16-37) and 18 (95 CI: 9.2-30) after CRT. Conclusions The PPV of routine registrations in the DNPR was moderate for first-time HF, high for most advanced HF treatments, and low for HF admissions after ICD or CRT. Thus, the DNPR is a valuable data source for population-based research on first-time HF and many advanced HF treatments. https://ijpds.org/article/view/2394Cardiac Surgical ProceduresEpidemiologyHeart FailurePredictive Value of TestsValidation Study |
| spellingShingle | Kasper Bonnesen Christoffer Witt Brian Løgstrup Hans Eiskjær Morten Schmidt Validity of heart failure diagnoses, treatments, and readmissions in the Danish National Patient Registry International Journal of Population Data Science Cardiac Surgical Procedures Epidemiology Heart Failure Predictive Value of Tests Validation Study |
| title | Validity of heart failure diagnoses, treatments, and readmissions in the Danish National Patient Registry |
| title_full | Validity of heart failure diagnoses, treatments, and readmissions in the Danish National Patient Registry |
| title_fullStr | Validity of heart failure diagnoses, treatments, and readmissions in the Danish National Patient Registry |
| title_full_unstemmed | Validity of heart failure diagnoses, treatments, and readmissions in the Danish National Patient Registry |
| title_short | Validity of heart failure diagnoses, treatments, and readmissions in the Danish National Patient Registry |
| title_sort | validity of heart failure diagnoses treatments and readmissions in the danish national patient registry |
| topic | Cardiac Surgical Procedures Epidemiology Heart Failure Predictive Value of Tests Validation Study |
| url | https://ijpds.org/article/view/2394 |
| work_keys_str_mv | AT kasperbonnesen validityofheartfailurediagnosestreatmentsandreadmissionsinthedanishnationalpatientregistry AT christofferwitt validityofheartfailurediagnosestreatmentsandreadmissionsinthedanishnationalpatientregistry AT brianløgstrup validityofheartfailurediagnosestreatmentsandreadmissionsinthedanishnationalpatientregistry AT hanseiskjær validityofheartfailurediagnosestreatmentsandreadmissionsinthedanishnationalpatientregistry AT mortenschmidt validityofheartfailurediagnosestreatmentsandreadmissionsinthedanishnationalpatientregistry |