Extremely rare case of H-type gallbladder duplication coexistent with carcinoma: a case report and review of the literature

Abstract Introduction Multiple gallbladders represent a rare congenital disorder, and coexistence with carcinoma is extremely rare, leading to a high possibility of misdiagnosis and surgical complications. In this study, a case was reported and the literature was reviewed. Case presentation An 80-ye...

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Main Authors: Takashi Furuhashi, Toshihiko Abe, Koichiro Sakata, Mayaka Noda, Tadafumi Fuchikami, Nobuhisa Ishikawa, Hiroyuki Fujito, Norihiro Onari, Tetsuo Hamada
Format: Article
Language:English
Published: Japan Surgical Society 2020-08-01
Series:Surgical Case Reports
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Online Access:http://link.springer.com/article/10.1186/s40792-020-00953-3
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author Takashi Furuhashi
Toshihiko Abe
Koichiro Sakata
Mayaka Noda
Tadafumi Fuchikami
Nobuhisa Ishikawa
Hiroyuki Fujito
Norihiro Onari
Tetsuo Hamada
author_facet Takashi Furuhashi
Toshihiko Abe
Koichiro Sakata
Mayaka Noda
Tadafumi Fuchikami
Nobuhisa Ishikawa
Hiroyuki Fujito
Norihiro Onari
Tetsuo Hamada
author_sort Takashi Furuhashi
collection DOAJ
description Abstract Introduction Multiple gallbladders represent a rare congenital disorder, and coexistence with carcinoma is extremely rare, leading to a high possibility of misdiagnosis and surgical complications. In this study, a case was reported and the literature was reviewed. Case presentation An 80-year-old woman was diagnosed with acute cholecystitis via ultrasonography and was successfully treated with antibiotics. After the patient’s biliary colic relapsed, she was referred to our hospital. Multiple imaging modalities revealed duplication of her gallbladder (H-type) and suggested coexistence with carcinoma. According to preoperative evaluations, we assumed the patient had stage IIIA disease, and cholecystectomy, cholangiography using a near-infrared ray vision system, and sectionectomy of segments 4a and 5 were performed. Contrary to the high standardized uptake values obtained by 18F-fluoro-2-deoxy-D-glucose positron emission tomography, gallbladder carcinoma was pathologically diagnosed as stage 0 mucosal cancer. Seven days after the operation, portal thrombosis of the posterior branch was revealed, and conservative therapy was indicated; satisfactory results were achieved. The patient was discharged 65 days after surgery. No recurrence was observed for 1 year after surgery. Conclusions An extremely rare case of malignancy in a duplicated gallbladder was reported, and the literature was reviewed. Accurate estimations are feasible for diagnoses of multiple gallbladders, where correct evaluations are vital, especially in malignant cases. Because of the possibility of malignancy, resected accessory gallbladders should be scrutinized pathologically.
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spelling doaj-art-97dda9dced2f4b279b9920323bec2faa2025-08-20T03:33:50ZengJapan Surgical SocietySurgical Case Reports2198-77932020-08-01611810.1186/s40792-020-00953-3Extremely rare case of H-type gallbladder duplication coexistent with carcinoma: a case report and review of the literatureTakashi Furuhashi0Toshihiko Abe1Koichiro Sakata2Mayaka Noda3Tadafumi Fuchikami4Nobuhisa Ishikawa5Hiroyuki Fujito6Norihiro Onari7Tetsuo Hamada8Department of Surgery, Japan Seafarers Relief Association Moji Ekisaikai HospitalDepartment of Surgery, Japan Seafarers Relief Association Moji Ekisaikai HospitalDepartment of Surgery, Japan Seafarers Relief Association Moji Ekisaikai HospitalDepartment of Gastroenterology, Japan Seafarers Relief Association Moji Ekisaikai HospitalDepartment of Gastroenterology, Japan Seafarers Relief Association Moji Ekisaikai HospitalDepartment of Gastroenterology, Japan Seafarers Relief Association Moji Ekisaikai HospitalDepartment of Gastroenterology, Japan Seafarers Relief Association Moji Ekisaikai HospitalDepartment of Radiology, Japan Seafarers Relief Association Moji Ekisaikai HospitalDepartment of Laboratory Medicine & Surgical pathology, Kyushu Railway Memorial HospitalAbstract Introduction Multiple gallbladders represent a rare congenital disorder, and coexistence with carcinoma is extremely rare, leading to a high possibility of misdiagnosis and surgical complications. In this study, a case was reported and the literature was reviewed. Case presentation An 80-year-old woman was diagnosed with acute cholecystitis via ultrasonography and was successfully treated with antibiotics. After the patient’s biliary colic relapsed, she was referred to our hospital. Multiple imaging modalities revealed duplication of her gallbladder (H-type) and suggested coexistence with carcinoma. According to preoperative evaluations, we assumed the patient had stage IIIA disease, and cholecystectomy, cholangiography using a near-infrared ray vision system, and sectionectomy of segments 4a and 5 were performed. Contrary to the high standardized uptake values obtained by 18F-fluoro-2-deoxy-D-glucose positron emission tomography, gallbladder carcinoma was pathologically diagnosed as stage 0 mucosal cancer. Seven days after the operation, portal thrombosis of the posterior branch was revealed, and conservative therapy was indicated; satisfactory results were achieved. The patient was discharged 65 days after surgery. No recurrence was observed for 1 year after surgery. Conclusions An extremely rare case of malignancy in a duplicated gallbladder was reported, and the literature was reviewed. Accurate estimations are feasible for diagnoses of multiple gallbladders, where correct evaluations are vital, especially in malignant cases. Because of the possibility of malignancy, resected accessory gallbladders should be scrutinized pathologically.http://link.springer.com/article/10.1186/s40792-020-00953-3Gallbladder duplicationAdenocarcinomaIntraoperative cholangiographyNear-infrared ray vision systemFDG-PET
spellingShingle Takashi Furuhashi
Toshihiko Abe
Koichiro Sakata
Mayaka Noda
Tadafumi Fuchikami
Nobuhisa Ishikawa
Hiroyuki Fujito
Norihiro Onari
Tetsuo Hamada
Extremely rare case of H-type gallbladder duplication coexistent with carcinoma: a case report and review of the literature
Surgical Case Reports
Gallbladder duplication
Adenocarcinoma
Intraoperative cholangiography
Near-infrared ray vision system
FDG-PET
title Extremely rare case of H-type gallbladder duplication coexistent with carcinoma: a case report and review of the literature
title_full Extremely rare case of H-type gallbladder duplication coexistent with carcinoma: a case report and review of the literature
title_fullStr Extremely rare case of H-type gallbladder duplication coexistent with carcinoma: a case report and review of the literature
title_full_unstemmed Extremely rare case of H-type gallbladder duplication coexistent with carcinoma: a case report and review of the literature
title_short Extremely rare case of H-type gallbladder duplication coexistent with carcinoma: a case report and review of the literature
title_sort extremely rare case of h type gallbladder duplication coexistent with carcinoma a case report and review of the literature
topic Gallbladder duplication
Adenocarcinoma
Intraoperative cholangiography
Near-infrared ray vision system
FDG-PET
url http://link.springer.com/article/10.1186/s40792-020-00953-3
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