Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis.
<h4>Objective</h4>To evaluate the effect of risk reduction interventions on HIV knowledge, attitudes and behaviors among men who have sex with men (MSM) in China.<h4>Methods</h4>We performed a systematic review and meta-analysis of HIV risk reduction intervention studies amon...
Saved in:
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0072747 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850115358305812480 |
|---|---|
| author | Hongyan Lu Yu Liu Kapil Dahiya Han-Zhu Qian Wensheng Fan Li Zhang Juntao Ma Yuhua Ruan Yiming Shao Sten H Vermund Lu Yin |
| author_facet | Hongyan Lu Yu Liu Kapil Dahiya Han-Zhu Qian Wensheng Fan Li Zhang Juntao Ma Yuhua Ruan Yiming Shao Sten H Vermund Lu Yin |
| author_sort | Hongyan Lu |
| collection | DOAJ |
| description | <h4>Objective</h4>To evaluate the effect of risk reduction interventions on HIV knowledge, attitudes and behaviors among men who have sex with men (MSM) in China.<h4>Methods</h4>We performed a systematic review and meta-analysis of HIV risk reduction intervention studies among Chinese MSM. The summary difference of standardized mean differences (SMD) between both study arms or between pre- and post-intervention assessments were defined as the effect size (ES); ES was calculated using standard meta-analysis in random effects models.<h4>Results</h4>Thirty-four eligible studies were included in the analysis, including two randomized clinical trials (RCT), six quasi-experimental studies, six pre-and-post intervention studies, and twenty serial cross-sectional intervention studies. These studies showed an increase in consistent condom use with any male sexual partners (mean ES, 0.46; 95% confidence interval [CI], 0.35-0.56), with regular sexual partners (mean ES, 0.41; 95% CI, 0.18-0.63), and casual sexual partners (mean ES, 0.52; 95% CI, 0.24-0.79). The analysis of ten studies that measured the impact on uptake of HIV testing also showed a positive result (mean ES, 0.55; 95% CI, 0.38-0.71). The risk reduction interventions also improved HIV/AIDS-related knowledge (mean ES, 0.77; 95% CI, 0.60-0.94) and attitudes (mean ES, 1.35; 95% CI, 0.91-1.79), but did not reduce prevalence of HIV (mean ES, 0.23; 95% CI, 0.02-0.45) and syphilis infections (mean ES, -0.01; 95% CI, -0.19-0.17). There was significant heterogeneity among these studies.<h4>Conclusions</h4>On aggregate, HIV risk reduction interventions were effective in reducing risky behaviors and improving knowledge and attitudes among Chinese MSM, but were not associated with a change in the prevalence of HIV and syphilis. Future studies should use incidence as definitive study outcome. |
| format | Article |
| id | doaj-art-97d5b1db4b7342e1987dd0e1b9ac93e4 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-97d5b1db4b7342e1987dd0e1b9ac93e42025-08-20T02:36:35ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0188e7274710.1371/journal.pone.0072747Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis.Hongyan LuYu LiuKapil DahiyaHan-Zhu QianWensheng FanLi ZhangJuntao MaYuhua RuanYiming ShaoSten H VermundLu Yin<h4>Objective</h4>To evaluate the effect of risk reduction interventions on HIV knowledge, attitudes and behaviors among men who have sex with men (MSM) in China.<h4>Methods</h4>We performed a systematic review and meta-analysis of HIV risk reduction intervention studies among Chinese MSM. The summary difference of standardized mean differences (SMD) between both study arms or between pre- and post-intervention assessments were defined as the effect size (ES); ES was calculated using standard meta-analysis in random effects models.<h4>Results</h4>Thirty-four eligible studies were included in the analysis, including two randomized clinical trials (RCT), six quasi-experimental studies, six pre-and-post intervention studies, and twenty serial cross-sectional intervention studies. These studies showed an increase in consistent condom use with any male sexual partners (mean ES, 0.46; 95% confidence interval [CI], 0.35-0.56), with regular sexual partners (mean ES, 0.41; 95% CI, 0.18-0.63), and casual sexual partners (mean ES, 0.52; 95% CI, 0.24-0.79). The analysis of ten studies that measured the impact on uptake of HIV testing also showed a positive result (mean ES, 0.55; 95% CI, 0.38-0.71). The risk reduction interventions also improved HIV/AIDS-related knowledge (mean ES, 0.77; 95% CI, 0.60-0.94) and attitudes (mean ES, 1.35; 95% CI, 0.91-1.79), but did not reduce prevalence of HIV (mean ES, 0.23; 95% CI, 0.02-0.45) and syphilis infections (mean ES, -0.01; 95% CI, -0.19-0.17). There was significant heterogeneity among these studies.<h4>Conclusions</h4>On aggregate, HIV risk reduction interventions were effective in reducing risky behaviors and improving knowledge and attitudes among Chinese MSM, but were not associated with a change in the prevalence of HIV and syphilis. Future studies should use incidence as definitive study outcome.https://doi.org/10.1371/journal.pone.0072747 |
| spellingShingle | Hongyan Lu Yu Liu Kapil Dahiya Han-Zhu Qian Wensheng Fan Li Zhang Juntao Ma Yuhua Ruan Yiming Shao Sten H Vermund Lu Yin Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis. PLoS ONE |
| title | Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis. |
| title_full | Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis. |
| title_fullStr | Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis. |
| title_full_unstemmed | Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis. |
| title_short | Effectiveness of HIV risk reduction interventions among men who have sex with men in China: a systematic review and meta-analysis. |
| title_sort | effectiveness of hiv risk reduction interventions among men who have sex with men in china a systematic review and meta analysis |
| url | https://doi.org/10.1371/journal.pone.0072747 |
| work_keys_str_mv | AT hongyanlu effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT yuliu effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT kapildahiya effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT hanzhuqian effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT wenshengfan effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT lizhang effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT juntaoma effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT yuhuaruan effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT yimingshao effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT stenhvermund effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis AT luyin effectivenessofhivriskreductioninterventionsamongmenwhohavesexwithmeninchinaasystematicreviewandmetaanalysis |