Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis

Aim: to present literature data on the importance of intra-abdominal hypertension in the pathogenesis of peritonitis.   Key points. Secondary purulent peritonitis is a severe and fairly common form of abdominal infection with high mortality. According to statistics, hospitalization of patients with...

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Main Authors: D. V. Cherdantsev, O. V. Ovchinnikova, Yu. G. Trofimovich, I. G. Noskov, O. V. Pervova, A. A. Kovalenko
Format: Article
Language:Russian
Published: Gastro LLC 2024-10-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/970
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author D. V. Cherdantsev
O. V. Ovchinnikova
Yu. G. Trofimovich
I. G. Noskov
O. V. Pervova
A. A. Kovalenko
author_facet D. V. Cherdantsev
O. V. Ovchinnikova
Yu. G. Trofimovich
I. G. Noskov
O. V. Pervova
A. A. Kovalenko
author_sort D. V. Cherdantsev
collection DOAJ
description Aim: to present literature data on the importance of intra-abdominal hypertension in the pathogenesis of peritonitis.   Key points. Secondary purulent peritonitis is a severe and fairly common form of abdominal infection with high mortality. According to statistics, hospitalization of patients with signs of local or diffuse peritonitis is more than 15 % among patients with acute surgical pathologies. One of the factors in the development of complications and an unfavorable prognosis for this disease is increased intra-abdominal pressure. To measure this indicator, a Foley catheter inserted into the bladder is used in medical practice. According to reference values, the optimal level of intra-abdominal pressure does not exceed 5 mmHg. A persistent increase in pressure of 12 mmHg and above indicates the development of intra-abdominal hypertension. An increase in the level of intra-abdominal pressure indicates the progression of the inflammatory destructive process in the abdominal cavity and contributes to the development of multiple organ failure with subsequent fatal outcome with untimely treatment. With an indicator exceeding 20 mmHg, there is a risk of developing abdominal compartment syndrome. This condition is characterized by increased pressure in two or more anatomical areas, which leads to decreased blood flow and subsequent tissue hypoxia. Intra-abdominal hypertension also increases the risk of developing postoperative peritonitis in patients who have undergone laparotomy.   Conclusion. To predict the course of secondary diffuse purulent peritonitis, reduce the risk of complications and mortality, it is necessary to focus on measuring intra-abdominal pressure as a mandatory manipulation in surgical patients. Despite its general availability and ease of implementation, this technique allows assessing the severity of organ dysfunctions.
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institution Kabale University
issn 1382-4376
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publishDate 2024-10-01
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-97cd186a88ef456f902b98862ed51f802025-02-10T16:14:39ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732024-10-01344424910.22416/1382-4376-2024-970-2913913Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent PeritonitisD. V. Cherdantsev0O. V. Ovchinnikova1Yu. G. Trofimovich2I. G. Noskov3O. V. Pervova4A. A. Kovalenko5Krasnoyarsk State Medical University named after Professor V.F. Voino-YasenetskyKrasnoyarsk State Medical University named after Professor V.F. Voino-YasenetskyKrasnoyarsk State Medical University named after Professor V.F. Voino-YasenetskyKrasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky; Krasnoyarsk District Clinical HospitalKrasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky; Krasnoyarsk District Clinical HospitalKrasnoyarsk State Medical University named after Professor V.F. Voino-YasenetskyAim: to present literature data on the importance of intra-abdominal hypertension in the pathogenesis of peritonitis.   Key points. Secondary purulent peritonitis is a severe and fairly common form of abdominal infection with high mortality. According to statistics, hospitalization of patients with signs of local or diffuse peritonitis is more than 15 % among patients with acute surgical pathologies. One of the factors in the development of complications and an unfavorable prognosis for this disease is increased intra-abdominal pressure. To measure this indicator, a Foley catheter inserted into the bladder is used in medical practice. According to reference values, the optimal level of intra-abdominal pressure does not exceed 5 mmHg. A persistent increase in pressure of 12 mmHg and above indicates the development of intra-abdominal hypertension. An increase in the level of intra-abdominal pressure indicates the progression of the inflammatory destructive process in the abdominal cavity and contributes to the development of multiple organ failure with subsequent fatal outcome with untimely treatment. With an indicator exceeding 20 mmHg, there is a risk of developing abdominal compartment syndrome. This condition is characterized by increased pressure in two or more anatomical areas, which leads to decreased blood flow and subsequent tissue hypoxia. Intra-abdominal hypertension also increases the risk of developing postoperative peritonitis in patients who have undergone laparotomy.   Conclusion. To predict the course of secondary diffuse purulent peritonitis, reduce the risk of complications and mortality, it is necessary to focus on measuring intra-abdominal pressure as a mandatory manipulation in surgical patients. Despite its general availability and ease of implementation, this technique allows assessing the severity of organ dysfunctions.https://www.gastro-j.ru/jour/article/view/970intra-abdominal hypertensiondiffuse purulent peritonitisintra-abdominal pressureabdominal compartment syndrome
spellingShingle D. V. Cherdantsev
O. V. Ovchinnikova
Yu. G. Trofimovich
I. G. Noskov
O. V. Pervova
A. A. Kovalenko
Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
intra-abdominal hypertension
diffuse purulent peritonitis
intra-abdominal pressure
abdominal compartment syndrome
title Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis
title_full Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis
title_fullStr Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis
title_full_unstemmed Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis
title_short Increased Intra-Abdominal Pressure as One of the Links in the Pathogenesis of Secondary Diffuse Purulent Peritonitis
title_sort increased intra abdominal pressure as one of the links in the pathogenesis of secondary diffuse purulent peritonitis
topic intra-abdominal hypertension
diffuse purulent peritonitis
intra-abdominal pressure
abdominal compartment syndrome
url https://www.gastro-j.ru/jour/article/view/970
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