Longitudinal trajectory of plasma p-tau217 in cognitively unimpaired subjects

Longitudinal trajectory of plasma p-tau217 in cognitively unimpaired subjects

Abstract Background The advent of Alzheimer’s disease-modifying drugs requires accurate biological diagnosis to identify candidates for these therapies. So far, the most promising single plasma biomarker is phosphorylated tau at threonine 217 (p-tau217). To understand its biological features, it is...

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Main Authors: Francisco Martínez-Dubarbie, Armando Guerra-Ruiz, Sara López-García, Carmen Lage, Marta Fernández-Matarrubia, Ana Pozueta-Cantudo, María García-Martínez, Andrea Corrales-Pardo, María Bravo, Marcos López-Hoyos, Juan Irure-Ventura, Enrique Marco de Lucas, Marta Drake-Pérez, María Teresa García-Unzueta, Pascual Sánchez-Juan, Eloy Rodríguez-Rodríguez
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Alzheimer’s Research & Therapy
Subjects:
Plasma p-tau217
Alzheimer’s Disease
Early diagnosis
Longitudinal
Healthy controls
Biomarkers
Online Access:https://doi.org/10.1186/s13195-024-01642-1
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