MiR-556-3p mediated repression of klotho under oxidative stress promotes fibrosis of renal tubular epithelial cells

Abstract Chronic kidney disease (CKD) is a global health issue characterized by renal fibrosis, which leads to irreversible tissue damage. Oxidative stress plays a key role in driving the fibrotic processes associated with CKD. This study investigates the roles of oxidative stress, miR-556-3p, and k...

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Bibliographic Details
Main Authors: Dong Zhang, Zongying Li, Yuan Gao, Hailing Sun
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85479-0
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